Seven patients with hematologic malignancies were treated with recombinant activated factor VII (rFVIIa) for severe bleeding episodes complicating diagnostic procedures or high-dose chemotherapy associated or not with stem cell transplantation. All patients were thrombocytopenic and refractory to standard support. After administration of rFVIIa, 2 complete responses, 3 partial responses and 2 failures were documented.

De Fabritiis, P., Dentamaro, T., Picardi, A., Cudillo, L., Masi, M., Amadori, S. (2004). Recombinant factor VIIa for the management of severe hemorrhages in patients with hematologic malignancies. HAEMATOLOGICA, 89(2), 243-245.

Recombinant factor VIIa for the management of severe hemorrhages in patients with hematologic malignancies

De Fabritiis, P;PICARDI, ALESSANDRA;CUDILLO, LAURA;AMADORI, SERGIO
2004-02-01

Abstract

Seven patients with hematologic malignancies were treated with recombinant activated factor VII (rFVIIa) for severe bleeding episodes complicating diagnostic procedures or high-dose chemotherapy associated or not with stem cell transplantation. All patients were thrombocytopenic and refractory to standard support. After administration of rFVIIa, 2 complete responses, 3 partial responses and 2 failures were documented.
feb-2004
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/15 - MALATTIE DEL SANGUE
English
Con Impact Factor ISI
Hematologic malignancies; Hemorrhages; rFVIIa; Stem cell transplantation
PMID: 15003905
De Fabritiis, P., Dentamaro, T., Picardi, A., Cudillo, L., Masi, M., Amadori, S. (2004). Recombinant factor VIIa for the management of severe hemorrhages in patients with hematologic malignancies. HAEMATOLOGICA, 89(2), 243-245.
De Fabritiis, P; Dentamaro, T; Picardi, A; Cudillo, L; Masi, M; Amadori, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/36777
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