In this paper we analysed clinical, laboratory characteristics and outcome of patients with haematological diseases who developed an Aspergillus niger infection, in a multicentre study involving 14 Italian Haematological Divisions during a 10-year period. The study recorded 194 consecutive microbiologically documented aspergilloses, eight of which (4%) were due to A. niger, and were observed only in five of the participating centres. The primary localization of infection was lung in seven cases and paranasal sinus in one case. Seven patients died at the end of follow-up. The death was mainly attributable to A. niger progression in six of them. Our study that collected the largest number of cases of A. niger infection in haematological malignancies confirms that this infrequent complication is characterized by a high mortality rate.

Fianchi L., P.M. (2004). Aspergillus niger infection in patients with haematological diseases: a report of eight cases. MYCOSES, 47, 163-167 [10.1111/j.1439-0507.2004.00960.x].

Aspergillus niger infection in patients with haematological diseases: a report of eight cases

CUDILLO, LAURA;
2004

Abstract

In this paper we analysed clinical, laboratory characteristics and outcome of patients with haematological diseases who developed an Aspergillus niger infection, in a multicentre study involving 14 Italian Haematological Divisions during a 10-year period. The study recorded 194 consecutive microbiologically documented aspergilloses, eight of which (4%) were due to A. niger, and were observed only in five of the participating centres. The primary localization of infection was lung in seven cases and paranasal sinus in one case. Seven patients died at the end of follow-up. The death was mainly attributable to A. niger progression in six of them. Our study that collected the largest number of cases of A. niger infection in haematological malignancies confirms that this infrequent complication is characterized by a high mortality rate.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/15 - Malattie del Sangue
English
Con Impact Factor ISI
Aspergillosis; Aspergillus niger; Leukaemia; Lung; Paranasal sinus; Pneumonia
Fianchi L., P.M. (2004). Aspergillus niger infection in patients with haematological diseases: a report of eight cases. MYCOSES, 47, 163-167 [10.1111/j.1439-0507.2004.00960.x].
Fianchi, L; Picardi, M; Cudillo, L; Corvatta, L; Mele, L; Trape, G; Girmenia, C; Pagano, L
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/35814
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