Although survival of encapsulated thymomas is usually good, some patients present a higher incidence rate of recurrence and a shorter long-term survival. Abnormalities in the components of cell cycle checkpoints are extremely common among virtually all neoplasms. In this study, three components of the cell cycle machinery (i.e., p21, p27 and p53) were examined in a series of well-characterized encapsulated thymoma specimens to analyze coregulation and influence on recurrence and survival.
Baldi, A., Ambrogi, V., Mineo, D., Mellone, P., Campioni, M., Citro, G., et al. (2005). Analysis of cell cycle regulator proteins in encapsulated thymomas. CLINICAL CANCER RESEARCH, 11(14), 5078-5083 [10.1158/1078-0432.CCR-05-0070].
Analysis of cell cycle regulator proteins in encapsulated thymomas
AMBROGI, VINCENZO;MINEO, DAVIDE;MINEO, TOMMASO CLAUDIO
2005-07-15
Abstract
Although survival of encapsulated thymomas is usually good, some patients present a higher incidence rate of recurrence and a shorter long-term survival. Abnormalities in the components of cell cycle checkpoints are extremely common among virtually all neoplasms. In this study, three components of the cell cycle machinery (i.e., p21, p27 and p53) were examined in a series of well-characterized encapsulated thymoma specimens to analyze coregulation and influence on recurrence and survival.| File | Dimensione | Formato | |
|---|---|---|---|
|
5.pdf
accesso aperto
Dimensione
352.07 kB
Formato
Adobe PDF
|
352.07 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
