The study of the complex web of interactions that link biological molecules in a cell is the subject of interactomics - currently one of the fastest moving fields in molecular biology. The recent completion of high-throughput studies to investigate systematically all the possible interactions in a variety of model organisms has provided unique opportunities to compare interaction networks and ask questions about their conservation during evolution. It is expected that this approach will yield a scientific return as rich as that obtained in the past decade from comparing genomes and proteomes from different organisms. © 2006 Elsevier Ltd. All rights reserved.

Kiemer, L., Cesareni, G. (2007). Comparative interactomics: comparing apples and pears?. TRENDS IN BIOTECHNOLOGY, 25(10), 448-454 [10.1016/j.tibtech.2007.08.002].

Comparative interactomics: comparing apples and pears?

CESARENI, GIOVANNI
2007-01-01

Abstract

The study of the complex web of interactions that link biological molecules in a cell is the subject of interactomics - currently one of the fastest moving fields in molecular biology. The recent completion of high-throughput studies to investigate systematically all the possible interactions in a variety of model organisms has provided unique opportunities to compare interaction networks and ask questions about their conservation during evolution. It is expected that this approach will yield a scientific return as rich as that obtained in the past decade from comparing genomes and proteomes from different organisms. © 2006 Elsevier Ltd. All rights reserved.
2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/18 - GENETICA
English
Genes; Mathematical models; Plant cell culture; Proteins; Comparative interactomics; Complex web; Interaction networks; Model organisms; Biomolecules; cell cycle protein; apple; Caenorhabditis elegans; comparative study; Drosophila melanogaster; genome; high throughput screening; molecular biology; nonhuman; nucleolus; pear; priority journal; proteomics; review; Saccharomyces cerevisiae; Animals; Evolution, Molecular; Gene Expression; Humans; Models, Biological; Plants; Protein Interaction Mapping; Proteins; Signal Transduction; Species Specificity; Pyrus
Kiemer, L., Cesareni, G. (2007). Comparative interactomics: comparing apples and pears?. TRENDS IN BIOTECHNOLOGY, 25(10), 448-454 [10.1016/j.tibtech.2007.08.002].
Kiemer, L; Cesareni, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/34936
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