Anti-HCV and HCV-RNA prevalence among adults from an isolated Central Italian community were 16.3% and 9.0%; 3.0%, 2.3% among 25-to-49-year-olds, 27.6%, 14.7% among older subjects. 1b genotype prevailed (88.5%). 1a, 1a/1b, 4 were also isolated. Seropositivity was associated with age >50 years, public dental health care, glass syringe use, surgical interventions. The transmission pattern seems to be shifting from that typical of Southern Italy (high prevalence, particularly in the elderly, 1b genotype predominant, various routes of transmission involved, cohort effect), to that typical of Europe (lower prevalence, particularly among younger adults, other genotypes involved, association with intravenous drug use and immigrants).
Petti, S., Divizia, M., Donia, D.t., D' Arca, A., Tarsitani, G., Fabi, G., et al. (2006). Analysis of the shift of the transmission pattern for hepatitis C in a community in Central Italy. NEW MICROBIOLOGICA, 29(3), 207-209.
Analysis of the shift of the transmission pattern for hepatitis C in a community in Central Italy
DIVIZIA, MAURIZIO;DONIA, DOMENICA TOMMASA;PANA', AUGUSTO
2006-01-01
Abstract
Anti-HCV and HCV-RNA prevalence among adults from an isolated Central Italian community were 16.3% and 9.0%; 3.0%, 2.3% among 25-to-49-year-olds, 27.6%, 14.7% among older subjects. 1b genotype prevailed (88.5%). 1a, 1a/1b, 4 were also isolated. Seropositivity was associated with age >50 years, public dental health care, glass syringe use, surgical interventions. The transmission pattern seems to be shifting from that typical of Southern Italy (high prevalence, particularly in the elderly, 1b genotype predominant, various routes of transmission involved, cohort effect), to that typical of Europe (lower prevalence, particularly among younger adults, other genotypes involved, association with intravenous drug use and immigrants).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
