Oxytetracycline (OXY) is a broad-range antimicrobial routinely used in pig production, at doses in the range of fewg/kg of medicated feed, during the weaning period. It could persist at ppm level in pig liquid manure that routinely is used for organic fertilisation. In the present work we describe a methodology to study OXY environmental fate in arable land where crops are cultivated for animal feeding purposes. A liquid-liquid extraction followed by metal chelate affinity chromatography was applied to environmental samples of manures and soils drawn within a case-control study. Extracts were then analysed by high performance liquid chromatography with UV/DAD detection, using a reverse phase column, and expressing the results as 4-epioxytetracycline epimer. Results indicate OXY is well retained at mg kg−1 levels in soil exposed to contaminated pig manure fertilisation. Such compartment could constitute an abiotic reservoir for the systemic and/or for the external contamination of corn.

Brambilla, G., Patrizii, M., Defilippis, S., Bonazzi, G., Mantovi, P., Barchi, D., et al. (2007). Oxytetracycline as environmental contaminant in arable lands. ANALYTICA CHIMICA ACTA, 586(1-2), 326-329 [10.1016/j.aca.2006.11.019].

Oxytetracycline as environmental contaminant in arable lands

MIGLIORE, LUCIANA
2007-01-01

Abstract

Oxytetracycline (OXY) is a broad-range antimicrobial routinely used in pig production, at doses in the range of fewg/kg of medicated feed, during the weaning period. It could persist at ppm level in pig liquid manure that routinely is used for organic fertilisation. In the present work we describe a methodology to study OXY environmental fate in arable land where crops are cultivated for animal feeding purposes. A liquid-liquid extraction followed by metal chelate affinity chromatography was applied to environmental samples of manures and soils drawn within a case-control study. Extracts were then analysed by high performance liquid chromatography with UV/DAD detection, using a reverse phase column, and expressing the results as 4-epioxytetracycline epimer. Results indicate OXY is well retained at mg kg−1 levels in soil exposed to contaminated pig manure fertilisation. Such compartment could constitute an abiotic reservoir for the systemic and/or for the external contamination of corn.
2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/07 - ECOLOGIA
English
Con Impact Factor ISI
Oxytetracycline; Manure contamination; Soil contamination
Brambilla, G., Patrizii, M., Defilippis, S., Bonazzi, G., Mantovi, P., Barchi, D., et al. (2007). Oxytetracycline as environmental contaminant in arable lands. ANALYTICA CHIMICA ACTA, 586(1-2), 326-329 [10.1016/j.aca.2006.11.019].
Brambilla, G; Patrizii, M; Defilippis, S; Bonazzi, G; Mantovi, P; Barchi, D; Migliore, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/34759
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