Background: To assess the accuracy of whole-body MR imaging (WB-MRI) in comparison with whole-body [18(F)]-2-fluoro-2-deoxy-d-glucose (FDG) PET-CT in staging patients with diagnosed colorectal carcinoma (CRC). Methods: Twenty consecutive patients with previously diagnosed CRC underwent WB-MRI (3T) and PET-CT for staging of lymph node (N) and distant metastases ( M). Evaluation was done according to the American Joint Committee on Cancer Staging Criteria. MR images were evaluated by two radiologists while PET-CT images by one radiologist and one nuclear medicine physician. Histology and/or a clinical follow-up of 3-6 months served as standard of reference. Results: Lymph node involvement was determined in 10/20 cases as N-positive in WB-MRI and in 15/20 in PETCT. M-stage was evaluated for liver metastases ( 27 lesions in 15 patients with WB-MRI, 23/15 patients with PET-CT), lung (19/5 patients with WB-MRI, 25/7 patients with PET-CT), and bone (9/3 patients with WB-MRI, 9/3 patients with PET-CT). Two patients showed peritoneal implants and three patients demonstrated local recurrence at the surgery site on both modalities. No brain metastases were found. Conclusions: WB-MRI is a feasible method for examining colon cancer patients but cannot displace the present role of PET-CT.

Squillaci, E., Manenti, G., Mancino, S., Ciccio, C., Calabria, F., Danieli, R., et al. (2008). Staging of colon cancer: whole-body MRI vs. whole-body PET-CT-initial clinical experience. ABDOMINAL IMAGING, 33(6), 676-688 [10.1007/s00261-007-9347-5].

Staging of colon cancer: whole-body MRI vs. whole-body PET-CT-initial clinical experience

SQUILLACI, ETTORE;MANENTI, GUGLIELMO;SCHILLACI, ORAZIO;SIMONETTI, GIOVANNI MARIA EGISTO
2008-01-01

Abstract

Background: To assess the accuracy of whole-body MR imaging (WB-MRI) in comparison with whole-body [18(F)]-2-fluoro-2-deoxy-d-glucose (FDG) PET-CT in staging patients with diagnosed colorectal carcinoma (CRC). Methods: Twenty consecutive patients with previously diagnosed CRC underwent WB-MRI (3T) and PET-CT for staging of lymph node (N) and distant metastases ( M). Evaluation was done according to the American Joint Committee on Cancer Staging Criteria. MR images were evaluated by two radiologists while PET-CT images by one radiologist and one nuclear medicine physician. Histology and/or a clinical follow-up of 3-6 months served as standard of reference. Results: Lymph node involvement was determined in 10/20 cases as N-positive in WB-MRI and in 15/20 in PETCT. M-stage was evaluated for liver metastases ( 27 lesions in 15 patients with WB-MRI, 23/15 patients with PET-CT), lung (19/5 patients with WB-MRI, 25/7 patients with PET-CT), and bone (9/3 patients with WB-MRI, 9/3 patients with PET-CT). Two patients showed peritoneal implants and three patients demonstrated local recurrence at the surgery site on both modalities. No brain metastases were found. Conclusions: WB-MRI is a feasible method for examining colon cancer patients but cannot displace the present role of PET-CT.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/36 - Diagnostica per Immagini e Radioterapia
English
Con Impact Factor ISI
Cancer staging; Colorectal carcinoma staging; Colorectal carcinoma metastasis; whole body PET; Whole-body MRI (WB-MRI)
Squillaci, E., Manenti, G., Mancino, S., Ciccio, C., Calabria, F., Danieli, R., et al. (2008). Staging of colon cancer: whole-body MRI vs. whole-body PET-CT-initial clinical experience. ABDOMINAL IMAGING, 33(6), 676-688 [10.1007/s00261-007-9347-5].
Squillaci, E; Manenti, G; Mancino, S; Ciccio, C; Calabria, F; Danieli, R; Schillaci, O; Simonetti, Gme
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/34613
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