background: to date, no study has specifically examined children with acute-onset pupillary motility disorders (APMD). especially in the emergency department (ED), it is crucial to distinguish benign and transient conditions from life-threatening or urgent conditions (UCs). the aim of the study is to describe the clinical characteristics of children with APMD and their association with an increased risk of UCs. methods: we conducted a pediatric retrospective study of APMD referred to ED over a 10-year period. We described the characteristics in the overall sample and in two subgroups divided according to urgency of the underlying condition. Furthermore, we applied a logistic regression model to identify the variables predictive of LT condition. Results: We analyzed 101 patients. In 59.4%, the APMD was isolated. In patients with extra-ocular involvement, the most frequently associated features were altered consciousness, headache, and vomiting. Exposure to toxic agents was reported in 48.5%. urgent conditions occurred significantly more frequently in older children, presenting bilateral APMD and/or other ocular or extra-ocular manifestations. conclusions: our study shows that UCs most commonly occur in patients presenting with bilateral APMD and other associated features. In unilateral/isolated APMD ophthalmological examination, exclusion of toxic exposure and observation until resolution of symptoms should be recommended.

Garone, G., Roversi, M., Pisani, M., La Penna, F., Musolino, A., Cristaldi, S., et al. (2023). Acute Pupillary Disorders in Children: A 10-Year Retrospective Study of 101 Patients. CHILDREN, 10(11) [10.3390/children10111739].

Acute Pupillary Disorders in Children: A 10-Year Retrospective Study of 101 Patients

Giacomo Garone;Marco Roversi;Antonio Musolino;ALBERTO VILLANI;
2023-01-01

Abstract

background: to date, no study has specifically examined children with acute-onset pupillary motility disorders (APMD). especially in the emergency department (ED), it is crucial to distinguish benign and transient conditions from life-threatening or urgent conditions (UCs). the aim of the study is to describe the clinical characteristics of children with APMD and their association with an increased risk of UCs. methods: we conducted a pediatric retrospective study of APMD referred to ED over a 10-year period. We described the characteristics in the overall sample and in two subgroups divided according to urgency of the underlying condition. Furthermore, we applied a logistic regression model to identify the variables predictive of LT condition. Results: We analyzed 101 patients. In 59.4%, the APMD was isolated. In patients with extra-ocular involvement, the most frequently associated features were altered consciousness, headache, and vomiting. Exposure to toxic agents was reported in 48.5%. urgent conditions occurred significantly more frequently in older children, presenting bilateral APMD and/or other ocular or extra-ocular manifestations. conclusions: our study shows that UCs most commonly occur in patients presenting with bilateral APMD and other associated features. In unilateral/isolated APMD ophthalmological examination, exclusion of toxic exposure and observation until resolution of symptoms should be recommended.
2023
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/38
English
children
miosis
mydriasis
pediatrics
pupillary motility
Garone, G., Roversi, M., Pisani, M., La Penna, F., Musolino, A., Cristaldi, S., et al. (2023). Acute Pupillary Disorders in Children: A 10-Year Retrospective Study of 101 Patients. CHILDREN, 10(11) [10.3390/children10111739].
Garone, G; Roversi, M; Pisani, M; La Penna, F; Musolino, A; Cristaldi, S; Maria Musolino, A; Roberto, A; Petrocelli, G; Reale, A; Midulla, F; Villani,...espandi
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Acute Pupillary Disorders in Children A 10-Year Retrospective Study of 101 Patients.pdf

accesso aperto

Tipologia: Versione Editoriale (PDF)
Licenza: Creative commons
Dimensione 526.39 kB
Formato Adobe PDF
526.39 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/346103
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact