Severe acute respiratory syndrome coronavirus 2 infection in children with autoimmune neutropenia may be a cause for concern. In this retrospective study, none of the 24 autoimmune neutropenia cases manifested severe coronavirus disease 2019. We found a significant improvement in neutrophils and a reduction in lymphocytes at post-infection follow-up compared with the median of previous values. We speculate that this paradoxical effect may be due to postinfection immunological phenomena.
Andrea Rotulo, G., Ceglie, G., Candino, A., Merola, A., Profeti, E., Giancotta, C., et al. (2023). The Clinical Course of SARS-CoV-2 Infection in Patients With Autoimmune Neutropenia: A Retrospective Case Series Study. THE PEDIATRIC INFECTIOUS DISEASE JOURNAL, 42(11), 403-406 [10.1097/INF.0000000000004093].
The Clinical Course of SARS-CoV-2 Infection in Patients With Autoimmune Neutropenia: A Retrospective Case Series Study
Giulia Ceglie;Annalisa Candino;Antonella Merola;Elisa Profeti;Stefania Mercadante;Nicola Cotugno;Giuseppe Palumbo;Andrea Finocchi
2023-11-01
Abstract
Severe acute respiratory syndrome coronavirus 2 infection in children with autoimmune neutropenia may be a cause for concern. In this retrospective study, none of the 24 autoimmune neutropenia cases manifested severe coronavirus disease 2019. We found a significant improvement in neutrophils and a reduction in lymphocytes at post-infection follow-up compared with the median of previous values. We speculate that this paradoxical effect may be due to postinfection immunological phenomena.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
