IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains similar to 2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.

Hermjakob, H., Montecchi Palazzi, L., Lewington, C., Mudali, S., Kerrien, S., Orchard, S., et al. (2004). IntAct: an open source molecular interaction database. NUCLEIC ACIDS RESEARCH, 32 [10.1093/nar/gkh052].

IntAct: an open source molecular interaction database

CESARENI, GIOVANNI;
2004-01-01

Abstract

IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains similar to 2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/18 - Genetica
English
Con Impact Factor ISI
protein; access to information; article; computer program; information retrieval; IntAct; model; molecular interaction; priority journal; protein database; protein interaction; scientific literature; SWISS-PROT; Animals; Computational Biology; Databases, Protein; Humans; Information Storage and Retrieval; Internet; Protein Binding; Proteins; Software; User-Computer Interface; Vocabulary, Controlled
Hermjakob, H., Montecchi Palazzi, L., Lewington, C., Mudali, S., Kerrien, S., Orchard, S., et al. (2004). IntAct: an open source molecular interaction database. NUCLEIC ACIDS RESEARCH, 32 [10.1093/nar/gkh052].
Hermjakob, H; Montecchi Palazzi, L; Lewington, C; Mudali, S; Kerrien, S; Orchard, S; Vingron, M; Roechert, B; Roepstorff, P; Valencia, A; Margalit, H; Armstrong, J; Bairoch, A; Cesareni, G; Sherman, D; Apweiler, R
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/32812
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