Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients.
Peppe, A., Gasbarra, A., Stefani, A., Chiavalon, C., Pierantozzi, M., Fermi, E., et al. (2008). Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?. PARKINSONISM & RELATED DISORDERS, 14(6), 501-504 [10.1016/j.parkreldis.2007.11.005].
Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?
STEFANI, ALESSANDRO;PIERANTOZZI, MARIANGELA;STANZIONE, PAOLO;CALTAGIRONE, CARLO;
2008-08-01
Abstract
Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients.| File | Dimensione | Formato | |
|---|---|---|---|
|
peppeParkn.pdf
solo utenti autorizzati
Licenza:
Non specificato
Dimensione
206.39 kB
Formato
Adobe PDF
|
206.39 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
