The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way.

Del Toro, N., Shrivastava, A., Ragueneau, E., Meldal, B., Combe, C., Barrera, E., et al. (2022). The IntAct database: efficient access to fine-grained molecular interaction data. NUCLEIC ACIDS RESEARCH, 50(D1), 648-653 [10.1093/nar/gkab1006].

The IntAct database: efficient access to fine-grained molecular interaction data

Perfetto, Livia;Licata, Luana;Iannuccelli, Marta;Panni, Simona;
2022-01-07

Abstract

The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way.
7-gen-2022
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/18 - GENETICA
English
Con Impact Factor ISI
Del Toro, N., Shrivastava, A., Ragueneau, E., Meldal, B., Combe, C., Barrera, E., et al. (2022). The IntAct database: efficient access to fine-grained molecular interaction data. NUCLEIC ACIDS RESEARCH, 50(D1), 648-653 [10.1093/nar/gkab1006].
Del Toro, N; Shrivastava, A; Ragueneau, E; Meldal, B; Combe, C; Barrera, E; Perfetto, L; How, K; Ratan, P; Shirodkar, G; Lu, O; Mészáros, B; Watkins, X; Pundir, S; Licata, L; Iannuccelli, M; Pellegrini, M; Martin, Mj; Panni, S; Duesbury, M; Vallet, Sd; Rappsilber, J; Ricard-Blum, S; Cesareni, G; Salwinski, L; Orchard, S; Porras, P; Panneerselvam, K; Hermjakob, H
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/325248
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