OBJECTIVESTo examine whether waist circumference (WC) and body-mass index (BMI) can predict long-term mortality in elderly subjects with and without chronic heart failure (CHF).DESIGNLongitudinal evaluation with a 12-year follow-up.SETTINGCampania, a region of southern Italy.PARTICIPANTSOne thousand three hundred thirty-two subjects aged 65 and older selected from the electoral rolls of Campania.MEASUREMENTSThe relationship between WC or BMI and mortality during a 12-year follow-up in 125 subjects with and 1,143 subjects without CHF.RESULTSMortality increased as WC increased in elderly subjects without CHF (from 47.8% to 56.7%, P=.01), and the increase was even greater in patients with CHF (from 58.1% to 82.0%, P=.01). In contrast, mortality decreased as BMI increased in elderly subjects without CHF (from 53.8% to 46.1%, P0 =.046) but not in those with CHF. According to Cox regression analysis, BMI protected against long-term mortality in the absence but not in the presence of CHF. In the absence of CHF, WC was associated with a 2% increased risk of long-term mortality for each 1-cm greater WC (Hazard Ratio (HR)=1.02, 95% confidence interval (CI)=1.01-1.03; P <.001), versus 5% increased in the presence of CHF (HR=1.06, 95% CI=1.02-1.10; P <.001).CONCLUSIONWC, but not BMI, is predictive of long-term mortality in elderly individuals with CHF and to a lesser extent in those without CHF.

Testa, G., Cacciatore, F., Galizia, G., Della-Morte, D., Mazzella, F., Langellotto, A., et al. (2010). Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(8), 1433-1440 [10.1111/j.1532-5415.2010.02979.x].

Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure

Della-Morte, David;Russo, Salvatore;
2010-08-01

Abstract

OBJECTIVESTo examine whether waist circumference (WC) and body-mass index (BMI) can predict long-term mortality in elderly subjects with and without chronic heart failure (CHF).DESIGNLongitudinal evaluation with a 12-year follow-up.SETTINGCampania, a region of southern Italy.PARTICIPANTSOne thousand three hundred thirty-two subjects aged 65 and older selected from the electoral rolls of Campania.MEASUREMENTSThe relationship between WC or BMI and mortality during a 12-year follow-up in 125 subjects with and 1,143 subjects without CHF.RESULTSMortality increased as WC increased in elderly subjects without CHF (from 47.8% to 56.7%, P=.01), and the increase was even greater in patients with CHF (from 58.1% to 82.0%, P=.01). In contrast, mortality decreased as BMI increased in elderly subjects without CHF (from 53.8% to 46.1%, P0 =.046) but not in those with CHF. According to Cox regression analysis, BMI protected against long-term mortality in the absence but not in the presence of CHF. In the absence of CHF, WC was associated with a 2% increased risk of long-term mortality for each 1-cm greater WC (Hazard Ratio (HR)=1.02, 95% confidence interval (CI)=1.01-1.03; P <.001), versus 5% increased in the presence of CHF (HR=1.06, 95% CI=1.02-1.10; P <.001).CONCLUSIONWC, but not BMI, is predictive of long-term mortality in elderly individuals with CHF and to a lesser extent in those without CHF.
ago-2010
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/09 - MEDICINA INTERNA
English
Con Impact Factor ISI
waist circumference
body mass index
chronic heart failure
mortality
Testa, G., Cacciatore, F., Galizia, G., Della-Morte, D., Mazzella, F., Langellotto, A., et al. (2010). Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(8), 1433-1440 [10.1111/j.1532-5415.2010.02979.x].
Testa, G; Cacciatore, F; Galizia, G; Della-Morte, D; Mazzella, F; Langellotto, A; Russo, S; Gargiulo, G; De Santis, D; Ferrara, N; Rengo, F; Abete, P...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/323203
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