: Diabetic retinopathy (DR), the most common microvascular complication of diabetes mellitus, represents the leading cause of acquired blindness in the working-age population. Due to the potential absence of symptoms in the early stages of the disease, the identification of clinical biomarkers can have a crucial role in the early diagnosis of DR as well as for the detection of prognostic factors. In particular, imaging techniques are fundamental tools for screening, diagnosis, classification, monitoring, treatment planning and prognostic assessment in DR. In this context, the identification of ocular and systemic biomarkers is crucial to facilitate the risk stratification of diabetic patients; moreover, reliable biomarkers could provide prognostic information on disease progression as well as assist in predicting a patient's response to therapy. In this context, this review aimed to provide an updated and comprehensive overview of the soluble and anatomical biomarkers associated with DR.

Ferrara, M., Loda, A., Coco, G., Grassi, P., Cestaro, S., Rezzola, S., et al. (2023). Diabetic retinopathy: soluble and imaging ocular biomarkers. JOURNAL OF CLINICAL MEDICINE, 12(3) [10.3390/jcm12030912].

Diabetic retinopathy: soluble and imaging ocular biomarkers

Coco, Giulia;
2023-01-24

Abstract

: Diabetic retinopathy (DR), the most common microvascular complication of diabetes mellitus, represents the leading cause of acquired blindness in the working-age population. Due to the potential absence of symptoms in the early stages of the disease, the identification of clinical biomarkers can have a crucial role in the early diagnosis of DR as well as for the detection of prognostic factors. In particular, imaging techniques are fundamental tools for screening, diagnosis, classification, monitoring, treatment planning and prognostic assessment in DR. In this context, the identification of ocular and systemic biomarkers is crucial to facilitate the risk stratification of diabetic patients; moreover, reliable biomarkers could provide prognostic information on disease progression as well as assist in predicting a patient's response to therapy. In this context, this review aimed to provide an updated and comprehensive overview of the soluble and anatomical biomarkers associated with DR.
24-gen-2023
Pubblicato
Rilevanza internazionale
Recensione
Esperti anonimi
Settore MED/30 - MALATTIE APPARATO VISIVO
English
Con Impact Factor ISI
confocal microscopy
corneal endothelial cell count
diabetic retinopathy
fluorescein angiography
ocular biomarkers diabetic retinopathy
optical coherence tomography
optical coherence tomography angiography
serum biomarkers diabetic retinopathy
ultra-widefield fundus photography
Ferrara, M., Loda, A., Coco, G., Grassi, P., Cestaro, S., Rezzola, S., et al. (2023). Diabetic retinopathy: soluble and imaging ocular biomarkers. JOURNAL OF CLINICAL MEDICINE, 12(3) [10.3390/jcm12030912].
Ferrara, M; Loda, A; Coco, G; Grassi, P; Cestaro, S; Rezzola, S; Romano, V; Semeraro, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/316279
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