Both the latest European guidelines on chronic coronary syndromes and the American guidelines on chest pain have underlined the importance of noninvasive imaging to select patients to be referred to invasive angiography. Nevertheless, although coronary stenosis has long been considered the main determinant of inducible ischemia and symptoms, growing evidence has demonstrated the importance of other underlying mechanisms (e.g., vasospasm, microvascular disease, energetic inefficiency). The search for a pathophysiology-driven treatment of these patients has therefore emerged as an important objective of multimodality imaging, integrating "anatomical" and "functional" information. We here provide an up-to-date guide for the choice and the interpretation of the currently available noninvasive anatomical and/or functional tests, focusing on emerging techniques (e.g., coronary flow velocity reserve, stress-cardiac magnetic resonance, hybrid imaging, functional-coronary computed tomography angiography, etc.), which could provide deeper pathophysiological insights to refine diagnostic and therapeutic pathways in the next future.

Morrone, D., Gentile, F., Aimo, A., Cameli, M., Barison, A., Elena Picoi, M., et al. (2022). Perspectives in noninvasive imaging for chronic coronary syndromes. INTERNATIONAL JOURNAL OF CARDIOLOGY, 365, 19-29.

Perspectives in noninvasive imaging for chronic coronary syndromes

Francesco Barillà;Saverio Muscoli;
2022-10-01

Abstract

Both the latest European guidelines on chronic coronary syndromes and the American guidelines on chest pain have underlined the importance of noninvasive imaging to select patients to be referred to invasive angiography. Nevertheless, although coronary stenosis has long been considered the main determinant of inducible ischemia and symptoms, growing evidence has demonstrated the importance of other underlying mechanisms (e.g., vasospasm, microvascular disease, energetic inefficiency). The search for a pathophysiology-driven treatment of these patients has therefore emerged as an important objective of multimodality imaging, integrating "anatomical" and "functional" information. We here provide an up-to-date guide for the choice and the interpretation of the currently available noninvasive anatomical and/or functional tests, focusing on emerging techniques (e.g., coronary flow velocity reserve, stress-cardiac magnetic resonance, hybrid imaging, functional-coronary computed tomography angiography, etc.), which could provide deeper pathophysiological insights to refine diagnostic and therapeutic pathways in the next future.
ott-2022
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE
English
Con Impact Factor ISI
CCTA; Cardiac magnetic resonance; Echocardiography; Imaging; Myocardial ischemia; Nuclear imaging
https://pubmed.ncbi.nlm.nih.gov/35901907/
Morrone, D., Gentile, F., Aimo, A., Cameli, M., Barison, A., Elena Picoi, M., et al. (2022). Perspectives in noninvasive imaging for chronic coronary syndromes. INTERNATIONAL JOURNAL OF CARDIOLOGY, 365, 19-29.
Morrone, D; Gentile, F; Aimo, A; Cameli, M; Barison, A; Elena Picoi, M; Guglielmo, M; Villano, A; Devita, A; Elena Mandoli, G; Concetta Pastore, M; Barillà, F; Mancone, M; Pedrinelli, R; Indolfi, C; Perrone Filardi, P; Muscoli, S; Tritto, I; Bergamaschi, L; Pizzi, C; A. Lanza., G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/314481
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