We report the case of C.L., an 8-year-old child who, following the surgical removal of an ependymoma from the left cerebral ventricle at the age of 4 years, developed significant difficulties in retaining day-to-day events and information. A thorough neuropsychological analysis documented in C.L. a severe anterograde amnesic syndrome, characterised by normal short-term memory, but poor performance on episodic long-term memory tests. In particular, C.L. demonstrated virtually no ability to recollect new verbal information several minutes after the presentation. As for semantic memory, C.L. demonstrated general semantic competencies, which, depending on the test, ranged from the level of a 6-year-old girl to a level corresponding to her actual chronological age. Finding a patient who, despite being severely impaired in the ability to recollect new episodic memories, still demonstrates at least partially preserved abilities to acquire new semantic knowledge suggests that neural circuits implicated in the memorisation of autobiographical events and factual information do not overlap completely. This case is examined in the light of growing literature concerned with the dissociation between episodic and semantic memory in childhood amnesia.

Vicari, S., Menghini, D., Di Paola, M., Serra, L., Donfrancesco, A., Fidani, P., et al. (2007). Acquired amnesia in childhood: a single case study. NEUROPSYCHOLOGIA, 45(4), 704-715 [10.1016/j.neuropsychologia.2006.08.004].

Acquired amnesia in childhood: a single case study

CARLESIMO, GIOVANNI
2007-03-02

Abstract

We report the case of C.L., an 8-year-old child who, following the surgical removal of an ependymoma from the left cerebral ventricle at the age of 4 years, developed significant difficulties in retaining day-to-day events and information. A thorough neuropsychological analysis documented in C.L. a severe anterograde amnesic syndrome, characterised by normal short-term memory, but poor performance on episodic long-term memory tests. In particular, C.L. demonstrated virtually no ability to recollect new verbal information several minutes after the presentation. As for semantic memory, C.L. demonstrated general semantic competencies, which, depending on the test, ranged from the level of a 6-year-old girl to a level corresponding to her actual chronological age. Finding a patient who, despite being severely impaired in the ability to recollect new episodic memories, still demonstrates at least partially preserved abilities to acquire new semantic knowledge suggests that neural circuits implicated in the memorisation of autobiographical events and factual information do not overlap completely. This case is examined in the light of growing literature concerned with the dissociation between episodic and semantic memory in childhood amnesia.
2-mar-2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Magnetic Resonance Imaging; Amnesia, Anterograde; Combined Modality Therapy; Fornix, Brain; Hippocampus; Humans; Brain Damage, Chronic; Reoperation; Cerebral Ventricle Neoplasms; Child; Dominance, Cerebral; Nerve Net; Ependymoma; Frontal Lobe; Verbal Learning; Memory, Short-Term; Postoperative Complications; Life Change Events; Retention (Psychology); Neuropsychological Tests; Image Processing, Computer-Assisted; Female
Vicari, S., Menghini, D., Di Paola, M., Serra, L., Donfrancesco, A., Fidani, P., et al. (2007). Acquired amnesia in childhood: a single case study. NEUROPSYCHOLOGIA, 45(4), 704-715 [10.1016/j.neuropsychologia.2006.08.004].
Vicari, S; Menghini, D; Di Paola, M; Serra, L; Donfrancesco, A; Fidani, P; Milano, G; Carlesimo, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/31398
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