purpose to evaluate if digital breast tomosynthesis spot compression view (DBT-SCV) could be an additional projection to confirm or deny architectural distortions (ADs) detected by digital breast tomosynthesis (DBT) while assessing the average glandular radiation dose. methods this is a retrospective cohort study enrolling 8864 DBT exams, of which only cases detecting primary AD and with BI-RADS 2-5 score were considered. seventy-one AD cases examined with DBT-SCV, US and MRI were evaluated for correlation in terms of BI-RADS score; variables among exams were assessed for inter-relationships. results Of all ADs identified at DBT, biopsy yielded malignancy in only 38%. PPV in identifying malignancy of ADs was higher for DBT-SCV than DBT (p < 0.05); the NPV of DBT-SCV was 94%. the difference between DBT and DBT-SCV in the detection of benign ADs was statistically significant (p < 0.05). AD without US or MRI confirmation was less likely to represent malignancy (p < 0.05). In detecting malignant cases of ADs, both DBT and DBT-SCV were strongly correlated with US and RM (Kappa > 0.90). In identifying benign cases of ADs, DBT-SCV was poorly/moderately correlated with US and RM (Kappa 0.25 and 0.66); DBT was negatively correlated with US and MRI. conclusion DBT-SCV could be useful to better characterize AD firstly identified by DBT, keeping dose levels within the reference limits. If AD is detected by DBT without an US or MRI correlate, that is not confirmed by DBT-SCV, a "wait and see " approach can be applied to reduce unnecessary biopsy.

Fiaschetti, V., Ubaldi, N., De Fazio, S., Ricci, A., Maspes, F., Cossu, E. (2023). Digital tomosynthesis spot view in architectural distortions: outcomes in management and radiation dose. LA RADIOLOGIA MEDICA, 35-48 [10.1007/s11547-022-01570-w].

Digital tomosynthesis spot view in architectural distortions: outcomes in management and radiation dose

Fiaschetti V.
;
Cossu E.
2023-01-01

Abstract

purpose to evaluate if digital breast tomosynthesis spot compression view (DBT-SCV) could be an additional projection to confirm or deny architectural distortions (ADs) detected by digital breast tomosynthesis (DBT) while assessing the average glandular radiation dose. methods this is a retrospective cohort study enrolling 8864 DBT exams, of which only cases detecting primary AD and with BI-RADS 2-5 score were considered. seventy-one AD cases examined with DBT-SCV, US and MRI were evaluated for correlation in terms of BI-RADS score; variables among exams were assessed for inter-relationships. results Of all ADs identified at DBT, biopsy yielded malignancy in only 38%. PPV in identifying malignancy of ADs was higher for DBT-SCV than DBT (p < 0.05); the NPV of DBT-SCV was 94%. the difference between DBT and DBT-SCV in the detection of benign ADs was statistically significant (p < 0.05). AD without US or MRI confirmation was less likely to represent malignancy (p < 0.05). In detecting malignant cases of ADs, both DBT and DBT-SCV were strongly correlated with US and RM (Kappa > 0.90). In identifying benign cases of ADs, DBT-SCV was poorly/moderately correlated with US and RM (Kappa 0.25 and 0.66); DBT was negatively correlated with US and MRI. conclusion DBT-SCV could be useful to better characterize AD firstly identified by DBT, keeping dose levels within the reference limits. If AD is detected by DBT without an US or MRI correlate, that is not confirmed by DBT-SCV, a "wait and see " approach can be applied to reduce unnecessary biopsy.
2023
Pubblicato
Rilevanza internazionale
Articolo
Comitato scientifico
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
Settore MEDS-22/A - Diagnostica per immagini e radioterapia
English
Con Impact Factor ISI
Architectural distortion
Average glandular dose
Digital breast tomosynthesis
Digital breast tomosynthesis spot compression view
Negative predictive value of digital breast tomosynthesis
Fiaschetti, V., Ubaldi, N., De Fazio, S., Ricci, A., Maspes, F., Cossu, E. (2023). Digital tomosynthesis spot view in architectural distortions: outcomes in management and radiation dose. LA RADIOLOGIA MEDICA, 35-48 [10.1007/s11547-022-01570-w].
Fiaschetti, V; Ubaldi, N; De Fazio, S; Ricci, A; Maspes, F; Cossu, E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/313858
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