Glutathione has long been suspected to be the primary low molecular weight compound present in all cells promoting the oxidative protein folding, but twenty years ago it was found "not guilty". Now, new surprising evidence repeats its request to be the "smoking gun" which reopens the criminal trial revealing the crucial involvement of this tripeptide.

Bocedi, A., Cattani, G., Gambardella, G., Schulte, L., Schwalbe, H., Ricci, G. (2021). Oxidative folding of proteins: the “smoking gun” of glutathione. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(18) [10.3390/ijms221810148].

Oxidative folding of proteins: the “smoking gun” of glutathione

Bocedi A.;Ricci G.
2021-01-01

Abstract

Glutathione has long been suspected to be the primary low molecular weight compound present in all cells promoting the oxidative protein folding, but twenty years ago it was found "not guilty". Now, new surprising evidence repeats its request to be the "smoking gun" which reopens the criminal trial revealing the crucial involvement of this tripeptide.
2021
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10 - BIOCHIMICA
English
cysteine reactivity; glutathione; glutathionylation; nitrosylation; oxidative folding; ribosomal exit tunnel; transient complex; Animals; Cysteine; Glutathione; Humans; Oxygen; Protein Processing, Post-Translational; Protein Folding
Bocedi, A., Cattani, G., Gambardella, G., Schulte, L., Schwalbe, H., Ricci, G. (2021). Oxidative folding of proteins: the “smoking gun” of glutathione. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(18) [10.3390/ijms221810148].
Bocedi, A; Cattani, G; Gambardella, G; Schulte, L; Schwalbe, H; Ricci, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/312072
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