Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this distinctive feature, finding 2 diagnoses of VEXAS among 24 cases with vacuoles.
Gurnari, C., Pagliuca, S., Durkin, L., Terkawi, L., Awada, H., Kongkiatkamon, S., et al. (2021). Vacuolization of hematopoietic precursors: an enigma with multiple etiologies. BLOOD, 137(26), 3685-3689 [10.1182/blood.2021010811].
Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
Gurnari, CarmeloWriting – Original Draft Preparation
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2021-07-01
Abstract
Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this distinctive feature, finding 2 diagnoses of VEXAS among 24 cases with vacuoles.File in questo prodotto:
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