PURPOSE OF REVIEW: human herpesvirus 8 is associated with neoplastic diseases in the immunocompromised host, including kaposi's sarcoma, multicentric castleman disease and primary effusion lymphoma. acquisition and control of human herpesvirus 8 infection have not yet been fully elucidated. this review focuses on the most recent findings on human herpesvirus 8 transmission. RECENT FINDINGS: Horizontal transmission by saliva appears the most common route not only in families in endemic regions, but also among high-risk groups in western countries. vertical, sexual, and blood and transplant-related transmission, however, remain of significant concern worldwide. novel approaches to standardize and optimize the assessment of human herpesvirus 8 infection have been reported. new insights on the host immune cell mechanisms devoted to the control of human herpesvirus 8 infection have also been presented. SUMMARY: the increasing knowledge about the routes of human herpesvirus 8 transmission, which appear now more similar to those of other more ubiquitous human herpesviruses (i.e. Epstein-Barr virus and cytomegalovirus), the growing efforts in improving laboratory diagnosis and the caution in the research of new biological associations are the major recent findings. they constitute a fundamental background for directing more appropriate future research and achieving more stringent evidence useful for the control of human herpesvirus 8 spread and for the management of human herpesvirus 8-related diseases.

Pica, F., Volpi, A. (2007). Transmission of human herpesvirus 8: An update. CURRENT OPINION IN INFECTIOUS DISEASES, 20(2), 152-156 [10.1097/QCO.0b013e3280143919].

Transmission of human herpesvirus 8: An update

PICA, FRANCESCA;VOLPI, ANTONIO
2007-01-01

Abstract

PURPOSE OF REVIEW: human herpesvirus 8 is associated with neoplastic diseases in the immunocompromised host, including kaposi's sarcoma, multicentric castleman disease and primary effusion lymphoma. acquisition and control of human herpesvirus 8 infection have not yet been fully elucidated. this review focuses on the most recent findings on human herpesvirus 8 transmission. RECENT FINDINGS: Horizontal transmission by saliva appears the most common route not only in families in endemic regions, but also among high-risk groups in western countries. vertical, sexual, and blood and transplant-related transmission, however, remain of significant concern worldwide. novel approaches to standardize and optimize the assessment of human herpesvirus 8 infection have been reported. new insights on the host immune cell mechanisms devoted to the control of human herpesvirus 8 infection have also been presented. SUMMARY: the increasing knowledge about the routes of human herpesvirus 8 transmission, which appear now more similar to those of other more ubiquitous human herpesviruses (i.e. Epstein-Barr virus and cytomegalovirus), the growing efforts in improving laboratory diagnosis and the caution in the research of new biological associations are the major recent findings. they constitute a fundamental background for directing more appropriate future research and achieving more stringent evidence useful for the control of human herpesvirus 8 spread and for the management of human herpesvirus 8-related diseases.
2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Blood transfusion; Human herpesvirus 8; Transmission; Transplantation; Vertical
Pica, F., Volpi, A. (2007). Transmission of human herpesvirus 8: An update. CURRENT OPINION IN INFECTIOUS DISEASES, 20(2), 152-156 [10.1097/QCO.0b013e3280143919].
Pica, F; Volpi, A
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Curr Opin Infect Dis 2007.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Licenza: Copyright dell'editore
Dimensione 168.54 kB
Formato Adobe PDF
168.54 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/31129
Citazioni
  • ???jsp.display-item.citation.pmc??? 32
  • Scopus 73
  • ???jsp.display-item.citation.isi??? 56
social impact