It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (- 950 to - 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.
Rogliani, P., Calzetta, L., Coppola, A., Puxeddu, E., Sergiacomi, G., D'Amato, D., et al. (2020). Are there pulmonary sequelae in patients recovering from COVID-19?. RESPIRATORY RESEARCH, 21(1), 286 [10.1186/s12931-020-01550-6].
Are there pulmonary sequelae in patients recovering from COVID-19?
Rogliani, Paola;Calzetta, Luigino;Puxeddu, Ermanno;Sergiacomi, Gianluigi;Orlacchio, Antonio
2020-10-30
Abstract
It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (- 950 to - 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.| File | Dimensione | Formato | |
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