Priapism is defined as a prolonged penile erection in absence of sexual arousal, leading also to serious sexual and urological problems such as erectile dysfunction and penile fibrosis. Amongst many different etiologies, priapism may be caused by a wide range of antipsychotic medications, mainly due to the α1-adrenergic receptor antagonism. On the other hand, only a couple of cases of opioid compounds have been linked to the onset of priapism, with evidence coming only from methadone and buprenorphine. Here we describe the case of a patient treated with antipsychotics who developed priapism four times following rapid discontinuation of buprenorphine/naloxone (Suboxone®).
Jannini, T.b., Di Lorenzo, G., Mariano, A., Santini, R., Ciocca, G., Jannini, E.a., et al. (2022). Buprenorphine/naloxone (Suboxone®) withdrawal may facilitate antipsychotic-induced priapism: a case report. RIVISTA DI PSICHIATRIA, 57(5), 246-250 [10.1708/3893.38747].
Buprenorphine/naloxone (Suboxone®) withdrawal may facilitate antipsychotic-induced priapism: a case report
Di Lorenzo, Giorgio
;Jannini, Emmanuele A;Siracusano, Alberto;Niolu, Cinzia
2022-01-01
Abstract
Priapism is defined as a prolonged penile erection in absence of sexual arousal, leading also to serious sexual and urological problems such as erectile dysfunction and penile fibrosis. Amongst many different etiologies, priapism may be caused by a wide range of antipsychotic medications, mainly due to the α1-adrenergic receptor antagonism. On the other hand, only a couple of cases of opioid compounds have been linked to the onset of priapism, with evidence coming only from methadone and buprenorphine. Here we describe the case of a patient treated with antipsychotics who developed priapism four times following rapid discontinuation of buprenorphine/naloxone (Suboxone®).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
