The surfaces of the human lymphoid cells of the line H9 chronically infected with the Human Immunodeficiency Virus HIV-1, and of human monocytes acutely infected in vitro with Mycobacterium Tuberculosis (MTB) were dried, fixed and imaged with atomic force microscopy (AFM). These images were compared with those of non-infected samples. Dried and fixed samples of infected cells can be distinguished from non-infected ones by AFM technology due to their different surface structures and by the presence of pathogenic (viz al or mycobacterial) agents on the cell surface.
Cricenti, A., Scarselli, M., Generosi, R., Perfetti, P., Bach, S., Colizzi, V. (1998). Analysis of infected human mononuclear cells by atomic force microscopy. NUOVO CIMENTO DELLA SOCIETÀ ITALIANA DI FISICA. D CONDENSED MATTER, ATOMIC, MOLECULAR AND CHEMICAL PHYSICS, BIOPHYSICS, 20(7-8), 1153-1162 [10.1007/BF03185525].
Analysis of infected human mononuclear cells by atomic force microscopy
Scarselli, MA;Colizzi, V
1998-01-01
Abstract
The surfaces of the human lymphoid cells of the line H9 chronically infected with the Human Immunodeficiency Virus HIV-1, and of human monocytes acutely infected in vitro with Mycobacterium Tuberculosis (MTB) were dried, fixed and imaged with atomic force microscopy (AFM). These images were compared with those of non-infected samples. Dried and fixed samples of infected cells can be distinguished from non-infected ones by AFM technology due to their different surface structures and by the presence of pathogenic (viz al or mycobacterial) agents on the cell surface.| File | Dimensione | Formato | |
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