When does modular control of locomotion emerge during human development? One view is that modularity is not innate, being learnt over several months of experience. Alternatively, the basic motor modules are present at birth, but are subsequently reconfigured due to changing brain-body-environment interactions. One problem in identifying modular structures in stepping infants is the presence of noise. Here, using both simulated and experimental muscle activity data from stepping neonates, infants, preschoolers, and adults, we dissect the influence of noise, and identify modular structures in all individuals, including neonates. Complexity of modularity increases from the neonatal stage to adulthood at multiple levels of the motor infrastructure, from the intrinsic rhythmicity measured at the level of individual muscles activities, to the level of muscle synergies and of bilateral intermuscular network connectivity. Low complexity and high variability of neuromuscular signals attest neonatal immaturity, but they also involve potential benefits for learning locomotor tasks.

Sylos-Labini, F., La Scaleia, V., Cappellini, G., Dewolf, A., Fabiano, A., Solopova, I.a., et al. (2022). Complexity of modular neuromuscular control increases and variability decreases during human locomotor development. COMMUNICATIONS BIOLOGY, 5(1) [10.1038/s42003-022-04225-8].

Complexity of modular neuromuscular control increases and variability decreases during human locomotor development

Sylos-Labini, Francesca
;
La Scaleia, Valentina;Cappellini, Germana;Lacquaniti, Francesco
Conceptualization
2022-11-16

Abstract

When does modular control of locomotion emerge during human development? One view is that modularity is not innate, being learnt over several months of experience. Alternatively, the basic motor modules are present at birth, but are subsequently reconfigured due to changing brain-body-environment interactions. One problem in identifying modular structures in stepping infants is the presence of noise. Here, using both simulated and experimental muscle activity data from stepping neonates, infants, preschoolers, and adults, we dissect the influence of noise, and identify modular structures in all individuals, including neonates. Complexity of modularity increases from the neonatal stage to adulthood at multiple levels of the motor infrastructure, from the intrinsic rhythmicity measured at the level of individual muscles activities, to the level of muscle synergies and of bilateral intermuscular network connectivity. Low complexity and high variability of neuromuscular signals attest neonatal immaturity, but they also involve potential benefits for learning locomotor tasks.
16-nov-2022
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/09 - FISIOLOGIA
English
Con Impact Factor ISI
Sylos-Labini, F., La Scaleia, V., Cappellini, G., Dewolf, A., Fabiano, A., Solopova, I.a., et al. (2022). Complexity of modular neuromuscular control increases and variability decreases during human locomotor development. COMMUNICATIONS BIOLOGY, 5(1) [10.1038/s42003-022-04225-8].
Sylos-Labini, F; La Scaleia, V; Cappellini, G; Dewolf, A; Fabiano, A; Solopova, Ia; Mondì, V; Ivanenko, Y; Lacquaniti, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/308636
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