Growing evidence emphasizes a positive role of brain ipsilesional (IL) reorganization in stroke patients with partial recovery. Ten patients affected by a monohemispheric stroke in the middle cerebral artery territory underwent functional magnetic resonance (IMRI) and magnetoencephalography (MEG) evaluation of the primary sensory (S I) activation via the same paradigm (median nerve galvanic stimulation). Four patients did not present S I fMRI activation [Rossini, P.M., Altamura, C., Ferretti, A., Vemieri, F., Zappasodi, F., Caulo, M., Pizzella, V, Del Gratta, C., Romani, G.L., Tecchio, F., 2004. Does cerebrovascular disease affect the coupling between neuronal activity and local haemodynamics? Brain 127, 99-110], although inclusion criteria required bilateral identifiable MEG responses. Mean Euclidean distance between IMRI and MEG SI activation Talairach coordinates was 10.1 +/- 2.9 mm, with a3D intra-class correlation (ICC) coefficient of 0.986. Interhemispheric asymmetries, evaluated by an MEG procedure independent of Talairach transformation, were outside or at the boundaries of reference ranges in 6 patients. In 3 of them, the IL activation presented medial or lateral shift with respect to the omega-shaped post-rolandic area while in the other 3, IL areas were outside the peri-rolandic region.In conclusion, despite dissociated intensity, the MEG and fMRI activations displayed good spatial consistency in stroke patients, thus confirming excessive interhemispheric asymmetries as a suitable indicator of unusual recruitments in the ipsilesional hemisphere, within or outside the peri-rolandic region. (c) 2006 Elsevier Inc. All rights reserved.

Altamura, C., Torquati, K., Zappasodi, F., Ferretti, A., Pizzella, V., Tibuzzi, F., et al. (2007). fMRI-vs-MEG evaluation of post-stroke interhemispheric asymmetries in primary sensorimotor hand areas. EXPERIMENTAL NEUROLOGY, 204(2), 631-639 [10.1016/j.expneurol.2006.12.017].

fMRI-vs-MEG evaluation of post-stroke interhemispheric asymmetries in primary sensorimotor hand areas

Landi, Doriana;
2007

Abstract

Growing evidence emphasizes a positive role of brain ipsilesional (IL) reorganization in stroke patients with partial recovery. Ten patients affected by a monohemispheric stroke in the middle cerebral artery territory underwent functional magnetic resonance (IMRI) and magnetoencephalography (MEG) evaluation of the primary sensory (S I) activation via the same paradigm (median nerve galvanic stimulation). Four patients did not present S I fMRI activation [Rossini, P.M., Altamura, C., Ferretti, A., Vemieri, F., Zappasodi, F., Caulo, M., Pizzella, V, Del Gratta, C., Romani, G.L., Tecchio, F., 2004. Does cerebrovascular disease affect the coupling between neuronal activity and local haemodynamics? Brain 127, 99-110], although inclusion criteria required bilateral identifiable MEG responses. Mean Euclidean distance between IMRI and MEG SI activation Talairach coordinates was 10.1 +/- 2.9 mm, with a3D intra-class correlation (ICC) coefficient of 0.986. Interhemispheric asymmetries, evaluated by an MEG procedure independent of Talairach transformation, were outside or at the boundaries of reference ranges in 6 patients. In 3 of them, the IL activation presented medial or lateral shift with respect to the omega-shaped post-rolandic area while in the other 3, IL areas were outside the peri-rolandic region.In conclusion, despite dissociated intensity, the MEG and fMRI activations displayed good spatial consistency in stroke patients, thus confirming excessive interhemispheric asymmetries as a suitable indicator of unusual recruitments in the ipsilesional hemisphere, within or outside the peri-rolandic region. (c) 2006 Elsevier Inc. All rights reserved.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26
English
Con Impact Factor ISI
stroke
fMRI
MEG
brain reorganization
recovery
brain mapping
Aged
Evoked Potentials, Somatosensory
Female
Functional Laterality
Hand
Humans
Image Processing, Computer-Assisted
Male
Middle Aged
Oxygen
Stroke
Magnetic Resonance Imaging
Magnetoencephalography
Somatosensory Cortex
Altamura, C., Torquati, K., Zappasodi, F., Ferretti, A., Pizzella, V., Tibuzzi, F., et al. (2007). fMRI-vs-MEG evaluation of post-stroke interhemispheric asymmetries in primary sensorimotor hand areas. EXPERIMENTAL NEUROLOGY, 204(2), 631-639 [10.1016/j.expneurol.2006.12.017].
Altamura, C; Torquati, K; Zappasodi, F; Ferretti, A; Pizzella, V; Tibuzzi, F; Vernieri, F; Pasqualetti, P; Landi, D; Del Gratta, C; Romani, G; Maria Rossini, P; Tecchio, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/306423
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