Background After the coronavirus disease 2019 outbreak, social isolation measures were introduced to contain infection. Although there is currently a slowing down of the infection, a reduction of hospitalizations, especially for myocardial infarction, was observed. The aim of our study is to evaluate the impact of the infectious disease on ST-segment-elevation myocardial infarction (STEMI) care during the coronavirus disease 2019 pandemic, through the analysis of recent cases of patients who underwent percutaneous coronary intervention. Methods and Results Consecutive patients affected by STEMI from March 1 to 31, 2020, during social restrictions of Italian government, were collected and compared with patients with STEMI treated during March 2019. During March 2020, we observed a 63% reduction of patients with STEMI who were admitted to our catheterization laboratory, when compared with the same period of 2019 (13 versus 35 patients). Changes in all time components of STEMI care were notably observed, particularly for longer median time in symptom-to-first medical contact, spoke-to-hub, and the cumulative symptom-to-wire delay. Procedural data and in-hospital outcomes were similar between the 2 groups, whereas the length of hospitalization was longer in patients of 2020. In this group, we also observed higher levels of cardiac biomarkers and a worse left ventricular ejection fraction at baseline and discharge. Conclusions The coronavirus disease 2019 outbreak induced a reduction of hospital access for STEMI with an increase in treatment delay, longer hospitalization, higher levels of cardiac biomarkers, and worse left ventricular function.

Cammalleri, V., Muscoli, S., Benedetto, D., Stifano, G., Macrini, M., Di Landro, A., et al. (2020). Who Has Seen Patients With ST-Segment-Elevation Myocardial Infarction? First Results From Italian Real-World Coronavirus Disease 2019. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 9(19), e017126 [10.1161/JAHA.120.017126].

Who Has Seen Patients With ST-Segment-Elevation Myocardial Infarction? First Results From Italian Real-World Coronavirus Disease 2019

Cammalleri, V;Muscoli, S;Di Luozzo, M;Mariano, EG;Sergi, D;De Vico, P;Romeo, F
2020

Abstract

Background After the coronavirus disease 2019 outbreak, social isolation measures were introduced to contain infection. Although there is currently a slowing down of the infection, a reduction of hospitalizations, especially for myocardial infarction, was observed. The aim of our study is to evaluate the impact of the infectious disease on ST-segment-elevation myocardial infarction (STEMI) care during the coronavirus disease 2019 pandemic, through the analysis of recent cases of patients who underwent percutaneous coronary intervention. Methods and Results Consecutive patients affected by STEMI from March 1 to 31, 2020, during social restrictions of Italian government, were collected and compared with patients with STEMI treated during March 2019. During March 2020, we observed a 63% reduction of patients with STEMI who were admitted to our catheterization laboratory, when compared with the same period of 2019 (13 versus 35 patients). Changes in all time components of STEMI care were notably observed, particularly for longer median time in symptom-to-first medical contact, spoke-to-hub, and the cumulative symptom-to-wire delay. Procedural data and in-hospital outcomes were similar between the 2 groups, whereas the length of hospitalization was longer in patients of 2020. In this group, we also observed higher levels of cardiac biomarkers and a worse left ventricular ejection fraction at baseline and discharge. Conclusions The coronavirus disease 2019 outbreak induced a reduction of hospital access for STEMI with an increase in treatment delay, longer hospitalization, higher levels of cardiac biomarkers, and worse left ventricular function.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/11
English
acute coronary syndrome
complications
coronavirus
interstitial pneumonia
percutaneous coronary intervention
Aged
COVID-19
Comorbidity
Coronavirus Infections
Echocardiography, Doppler, Color
Electrocardiography
Female
Follow-Up Studies
Heart Ventricles
Hospital Mortality
Hospitalization
Humans
Incidence
Italy
Male
Middle Aged
Pandemics
Percutaneous Coronary Intervention
Pneumonia, Viral
Prognosis
Retrospective Studies
SARS-CoV-2
ST Elevation Myocardial Infarction
Stroke Volume
Survival Rate
Betacoronavirus
Cammalleri, V., Muscoli, S., Benedetto, D., Stifano, G., Macrini, M., Di Landro, A., et al. (2020). Who Has Seen Patients With ST-Segment-Elevation Myocardial Infarction? First Results From Italian Real-World Coronavirus Disease 2019. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 9(19), e017126 [10.1161/JAHA.120.017126].
Cammalleri, V; Muscoli, S; Benedetto, D; Stifano, G; Macrini, M; Di Landro, A; Di Luozzo, M; Marchei, M; Mariano, E; Cota, L; Sergi, D; Bezzeccheri, A; Bonanni, M; Baluci, M; De Vico, P; Romeo, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/304996
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