Objectives To test the efficacy of maternal activity restriction for reducing peripheral vascular resistance in normotensive pregnant women with raised total vascular resistance (TVR) and to evaluate its effect on fetal growth.Methods This was a prospective case-control study of 30 women enrolled between 27 and 29weeks' gestation. All patients met the following criteria: normal blood pressure before and during pregnancy, TVR between 1300 and 1400 dynes x s/cm(5) at enrolment, normal fetal Doppler parameters at enrolment and abdominal circumference between the 10(th) and 25(th) centiles. Patients were assigned to activity restriction (activity-restriction group; n=15) or no treatment (control group; n=15) and were assessed after 4weeks for TVR and fetal growth.Results TVR at enrolment and estimated fetal weight centile were similar in the activity-restriction group vs controls (1358 +/- 26 vs 1353 +/- 30 dynesxs/cm(5); 18th +/- 4 vs 19th +/- 4 centile; P = NS). After 4 weeks, the activity-restriction group compared with controls showed significantly lower TVR (1165 +/- 159 vs 1314 +/- 190 dynes x s/cm(5); P < 0.05), which was associated with higher estimated fetal weight centile (25th +/- 5 vs 20th +/- 5 centile; P < 0.05). TVR was lower and estimated fetal weight centile higher for the activity-restriction group after 4weeks compared with at enrolment.Conclusions In normotensive pregnant women with raised TVR, maternal activity restriction appears to be effective in reducing TVR and therefore enhancing fetal growth. Copyright (C) 2017 ISUOG. Published by John Wiley & Sons Ltd.

Vasapollo, B., Lo Presti, D., Gagliardi, G., Farsetti, D., Tiralongo, G.m., Pisani, I., et al. (2018). Restricted physical activity in pregnancy reduces maternal vascular resistance and improves fetal growth. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 51(5), 672-676 [10.1002/uog.17489].

Restricted physical activity in pregnancy reduces maternal vascular resistance and improves fetal growth

Farsetti D.;Valensise H.
2018

Abstract

Objectives To test the efficacy of maternal activity restriction for reducing peripheral vascular resistance in normotensive pregnant women with raised total vascular resistance (TVR) and to evaluate its effect on fetal growth.Methods This was a prospective case-control study of 30 women enrolled between 27 and 29weeks' gestation. All patients met the following criteria: normal blood pressure before and during pregnancy, TVR between 1300 and 1400 dynes x s/cm(5) at enrolment, normal fetal Doppler parameters at enrolment and abdominal circumference between the 10(th) and 25(th) centiles. Patients were assigned to activity restriction (activity-restriction group; n=15) or no treatment (control group; n=15) and were assessed after 4weeks for TVR and fetal growth.Results TVR at enrolment and estimated fetal weight centile were similar in the activity-restriction group vs controls (1358 +/- 26 vs 1353 +/- 30 dynesxs/cm(5); 18th +/- 4 vs 19th +/- 4 centile; P = NS). After 4 weeks, the activity-restriction group compared with controls showed significantly lower TVR (1165 +/- 159 vs 1314 +/- 190 dynes x s/cm(5); P < 0.05), which was associated with higher estimated fetal weight centile (25th +/- 5 vs 20th +/- 5 centile; P < 0.05). TVR was lower and estimated fetal weight centile higher for the activity-restriction group after 4weeks compared with at enrolment.Conclusions In normotensive pregnant women with raised TVR, maternal activity restriction appears to be effective in reducing TVR and therefore enhancing fetal growth. Copyright (C) 2017 ISUOG. Published by John Wiley & Sons Ltd.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/40
English
activity restriction
bed rest
fetal growth
maternal echocardiography
maternal hemodynamics
total vascular resistance
Adult
Birth Weight
Case-Control Studies
Exercise
Female
Fetal Development
Fetal Growth Retardation
Gestational Age
Humans
Infant, Newborn
Pregnancy
Prospective Studies
Ultrasonography, Prenatal
Vascular Resistance
Vasapollo, B., Lo Presti, D., Gagliardi, G., Farsetti, D., Tiralongo, G.m., Pisani, I., et al. (2018). Restricted physical activity in pregnancy reduces maternal vascular resistance and improves fetal growth. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 51(5), 672-676 [10.1002/uog.17489].
Vasapollo, B; Lo Presti, D; Gagliardi, G; Farsetti, D; Tiralongo, Gm; Pisani, I; Novelli, Gp; Valensise, H
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/303744
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