Objectives To improve identification of fetal growth restriction (FGR) by means of umbilical venous flow (QUV) and maternal hemodynamics, including systemic vascular resistance (SVR) and cardiac output (CO), in order to distinguish between FGR and SGA. Methods We enrolled 68 pregnancies (36 SGA, 8 early FGR and 24 late FGR) who underwent a complete fetal hemodynamic examination including QUV and a noninvasive maternal hemodynamics assessment by means of USCOM. Results In comparison with SGA, QUV and corrected for estimated fetal weight QUV (cQUV) were significantly lower in early and late-FGR. In addition, maternal CO was lower in early and late-FGR, while SVR was lower only in early-onset FGR. According to ROC analysis, cQUV centile (AUC 0.92, 0.72) was the best parameter for the prediction of SGA before and after 32 weeks, followed by SVR and CO. For all parameters, the prediction was always better in the case of early-onset FGR Conclusions UV flow and maternal hemodynamics examination are useful tools to accurately discern between SGA and FGR.

Farsetti, D., Pometti, F., Maria Tiralongo, G., Lo Presti, D., Pisani, I., Gagliardi, G., et al. (2021). Distinction between SGA and FGR by means of fetal umbilical vein flow and maternal hemodynamics. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 1-7 [10.1080/14767058.2021.1918091].

Distinction between SGA and FGR by means of fetal umbilical vein flow and maternal hemodynamics

Daniele Farsetti
;
Herbert Valensise
2021

Abstract

Objectives To improve identification of fetal growth restriction (FGR) by means of umbilical venous flow (QUV) and maternal hemodynamics, including systemic vascular resistance (SVR) and cardiac output (CO), in order to distinguish between FGR and SGA. Methods We enrolled 68 pregnancies (36 SGA, 8 early FGR and 24 late FGR) who underwent a complete fetal hemodynamic examination including QUV and a noninvasive maternal hemodynamics assessment by means of USCOM. Results In comparison with SGA, QUV and corrected for estimated fetal weight QUV (cQUV) were significantly lower in early and late-FGR. In addition, maternal CO was lower in early and late-FGR, while SVR was lower only in early-onset FGR. According to ROC analysis, cQUV centile (AUC 0.92, 0.72) was the best parameter for the prediction of SGA before and after 32 weeks, followed by SVR and CO. For all parameters, the prediction was always better in the case of early-onset FGR Conclusions UV flow and maternal hemodynamics examination are useful tools to accurately discern between SGA and FGR.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/40
English
Fetal growth restriction
cardiac output
maternal hemodynamics
small for gestational age
systemic vascular resistance
umbilical vein blood flow
Farsetti, D., Pometti, F., Maria Tiralongo, G., Lo Presti, D., Pisani, I., Gagliardi, G., et al. (2021). Distinction between SGA and FGR by means of fetal umbilical vein flow and maternal hemodynamics. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 1-7 [10.1080/14767058.2021.1918091].
Farsetti, D; Pometti, F; Maria Tiralongo, G; Lo Presti, D; Pisani, I; Gagliardi, G; Vasapollo, B; Paolo Novelli, G; Valensise, Hcc
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/303654
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