IntroductionMany investigations showed that platelet-rich plasma (PRP), human follicles stem cells (HFSCs), and adipose-derived stem cells (ASCs), considered autologous stem cell-based therapy (ASC-BT), are effective for hair regrowth (HR) in patients affected by androgenetic alopecia and for wound healing (WH). The aim of this article is to analyze the in vitro and in vivo impact of different PRP, HFSCs, and ASCs preparation methods on HR and in WH.Areas CoveredThe analyzed data intended to clarify the molecular mechanism in which PRP, HFSCs, and ASCs are involved, the clinical use and related indications, fully respecting the European rules. Comparative studies between different systems of PRP, HFSCs, and ASCs preparation revealed differences in terms of HR and WH.Expert OpinionDespite a lack of standardized protocols, there is convincing evidence with objective measurement modalities that display positive outcomes of ASC-BT in HR and WH.

Gentile, P., Alves, R., Cole, J.p., Andjelkov, K., Van Helmelryck, T., Fernandez, J., et al. (2021). AIRMESS - Academy of International Regenerative Medicine & Surgery Societies: recommendations in the use of platelet-rich plasma (PRP), autologous stem cell-based therapy (ASC-BT) in androgenetic alopecia and wound healing. EXPERT OPINION ON BIOLOGICAL THERAPY, 21(11), 1443-1449 [10.1080/14712598.2021.1908995].

AIRMESS - Academy of International Regenerative Medicine & Surgery Societies: recommendations in the use of platelet-rich plasma (PRP), autologous stem cell-based therapy (ASC-BT) in androgenetic alopecia and wound healing

Gentile, Pietro
Writing – Original Draft Preparation
;
2021

Abstract

IntroductionMany investigations showed that platelet-rich plasma (PRP), human follicles stem cells (HFSCs), and adipose-derived stem cells (ASCs), considered autologous stem cell-based therapy (ASC-BT), are effective for hair regrowth (HR) in patients affected by androgenetic alopecia and for wound healing (WH). The aim of this article is to analyze the in vitro and in vivo impact of different PRP, HFSCs, and ASCs preparation methods on HR and in WH.Areas CoveredThe analyzed data intended to clarify the molecular mechanism in which PRP, HFSCs, and ASCs are involved, the clinical use and related indications, fully respecting the European rules. Comparative studies between different systems of PRP, HFSCs, and ASCs preparation revealed differences in terms of HR and WH.Expert OpinionDespite a lack of standardized protocols, there is convincing evidence with objective measurement modalities that display positive outcomes of ASC-BT in HR and WH.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/19
English
Con Impact Factor ISI
ASCS
HFSC
PRP in androgenetic alopecia
PRP in hair loss
Plastic surgery
adipose-derived stem cells
hair regrowth
human follicle stem cells
platelet-rich plasma
regenerative plastic surgery
wound healing
Alopecia
Humans
Stem Cells
Wound Healing
Platelet-Rich Plasma
Regenerative Medicine
Gentile, P., Alves, R., Cole, J.p., Andjelkov, K., Van Helmelryck, T., Fernandez, J., et al. (2021). AIRMESS - Academy of International Regenerative Medicine & Surgery Societies: recommendations in the use of platelet-rich plasma (PRP), autologous stem cell-based therapy (ASC-BT) in androgenetic alopecia and wound healing. EXPERT OPINION ON BIOLOGICAL THERAPY, 21(11), 1443-1449 [10.1080/14712598.2021.1908995].
Gentile, P; Alves, R; Cole, Jp; Andjelkov, K; Van Helmelryck, T; Fernandez, J; Trivisonno, A; Guillaume, L; Verpaele, A; Tonnard, P; Magalon, J; Magalon, G; Menkes, S
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/303522
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