Background: To date, there are no data regarding the systematic application of Point-of-Care Lung Ultrasound (PoC-LUS) in children with Multisystem Inflammatory Syndrome in Children (MIS-C). The main aim of this study is to show the role of Point-of-Care Lung Ultrasound as an additional aid in the diagnosis of COVID-19-related Multisystem Inflammatory Syndrome in Children (MIS-C). Methods: Between April 2020 and April 2021, patients aged 0-18 years referred to our emergency department for fever, and later hospitalized without a specific diagnosis, underwent PoC-LUS. Ultrasound images of patients with a final diagnosis of MIS-C were retrospectively evaluated. Results: Ten patients were enrolled. All were described to have pleural irregularities and B-lines. In particular: 8/10 children presented with isolated B-lines in at least half of the lung areas of interest; 8/10 presented with multiple B-lines and 3/8 had them in at least 50% of lung areas; 5/10 had a white lung appearance in at least one lung area and 1/5 had them in half of the areas of interest. Pleural effusion was described in 9/10. Conclusions: During the ongoing COVID-19 pandemic, we suggest performing PoC-LUS in febrile patients with high levels of inflammatory indices and clinical suspicion of MIS-C, or without a certain diagnosis; the finding of many B-lines and pleural effusion would support the diagnosis of a systemic inflammatory disease.

Musolino, A.m., Boccuzzi, E., Buonsenso, D., Supino, M.c., Mesturino, M.a., Pitaro, E., et al. (2022). The role of lung ultrasound in diagnosing COVID-19-related multisystemic inflammatory disease: A preliminary experience. JOURNAL OF CLINICAL MEDICINE, 11(1), 234 [10.3390/jcm11010234].

The role of lung ultrasound in diagnosing COVID-19-related multisystemic inflammatory disease: A preliminary experience

Sinibaldi S.;Palma P.;Villani A.;
2022-01-01

Abstract

Background: To date, there are no data regarding the systematic application of Point-of-Care Lung Ultrasound (PoC-LUS) in children with Multisystem Inflammatory Syndrome in Children (MIS-C). The main aim of this study is to show the role of Point-of-Care Lung Ultrasound as an additional aid in the diagnosis of COVID-19-related Multisystem Inflammatory Syndrome in Children (MIS-C). Methods: Between April 2020 and April 2021, patients aged 0-18 years referred to our emergency department for fever, and later hospitalized without a specific diagnosis, underwent PoC-LUS. Ultrasound images of patients with a final diagnosis of MIS-C were retrospectively evaluated. Results: Ten patients were enrolled. All were described to have pleural irregularities and B-lines. In particular: 8/10 children presented with isolated B-lines in at least half of the lung areas of interest; 8/10 presented with multiple B-lines and 3/8 had them in at least 50% of lung areas; 5/10 had a white lung appearance in at least one lung area and 1/5 had them in half of the areas of interest. Pleural effusion was described in 9/10. Conclusions: During the ongoing COVID-19 pandemic, we suggest performing PoC-LUS in febrile patients with high levels of inflammatory indices and clinical suspicion of MIS-C, or without a certain diagnosis; the finding of many B-lines and pleural effusion would support the diagnosis of a systemic inflammatory disease.
2022
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
English
lung ultrasound
multisystem inflammatory syndrome
children
Musolino, A.m., Boccuzzi, E., Buonsenso, D., Supino, M.c., Mesturino, M.a., Pitaro, E., et al. (2022). The role of lung ultrasound in diagnosing COVID-19-related multisystemic inflammatory disease: A preliminary experience. JOURNAL OF CLINICAL MEDICINE, 11(1), 234 [10.3390/jcm11010234].
Musolino, Am; Boccuzzi, E; Buonsenso, D; Supino, Mc; Mesturino, Ma; Pitaro, E; Ferro, V; Nacca, R; Sinibaldi, S; Palma, P; Villani, A; Toma, P...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/299758
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