TNF-alpha levels are increased in obesity and type 2 diabetes. The regulation of TNF-alpha converting enzyme (TACE) and its inhibitor, tissue inhibitor of metalloproteinase 3 (TIMP3), in human type 2 diabetes is unknown.

Monroy, A., Kamath, S., Chavez, A., Centonze, V., Veerasamy, M., Barrentine, A., et al. (2009). Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans. DIABETOLOGIA, 52(10), 2169-2181 [10.1007/s00125-009-1451-3].

Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans

FEDERICI, MASSIMO;
2009-10-01

Abstract

TNF-alpha levels are increased in obesity and type 2 diabetes. The regulation of TNF-alpha converting enzyme (TACE) and its inhibitor, tissue inhibitor of metalloproteinase 3 (TIMP3), in human type 2 diabetes is unknown.
ott-2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore M-EDF/01 - METODI E DIDATTICHE DELLE ATTIVITA' MOTORIE
English
Con Impact Factor ISI
Humans; Muscle, Skeletal; Receptors, Interleukin-6; Blotting, Western; Tissue Inhibitor of Metalloproteinase-3; ADAM Proteins; Adult; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Insulin Resistance; Female; Male
Monroy, A., Kamath, S., Chavez, A., Centonze, V., Veerasamy, M., Barrentine, A., et al. (2009). Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans. DIABETOLOGIA, 52(10), 2169-2181 [10.1007/s00125-009-1451-3].
Monroy, A; Kamath, S; Chavez, A; Centonze, V; Veerasamy, M; Barrentine, A; Wewer, J; Coletta, D; Jenkinson, C; Jhingan, R; Smokler, D; Reyna, S; Musi, N; Khokka, R; Federici, M; Tripathy, D; Defronzo, R; Folli, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/29771
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