This report describes the case of a young Romanian patient who developed a severe exacerbation of pulmonary tuberculosis during interferon-alpha treatment for chronic hepatitis D. While this occurrence underscores that clinical guidelines should be applied with caution in immigrants from underdeveloped countries, due to the possible presence of unrecognized or unreported comorbidity, the mechanisms for an interferon-related exacerbation of pulmonary tuberculosis are also examined. We propose that IFN-induced weight loss and anorexia may have played an important role in promoting clinical manifestations of tuberculosis in our patient. © 2007 The British Infection Society.
Telesca, C., ANGELICO, M., Piccolo, P., Nosotti, L., Morrone, A., Longhi, C., et al. (2007). Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant. JOURNAL OF INFECTION, 54(4), e223-e226.
Tipologia: | Articolo su rivista |
Citazione: | Telesca, C., ANGELICO, M., Piccolo, P., Nosotti, L., Morrone, A., Longhi, C., et al. (2007). Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant. JOURNAL OF INFECTION, 54(4), e223-e226. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/12 - Gastroenterologia |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.jinf.2006.12.009 |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | 2007 |
Titolo: | Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant |
Autori: | |
Autori: | Telesca, C; ANGELICO, M; Piccolo, P; Nosotti, L; Morrone, A; Longhi, C; Carbone, M; BAIOCCHI, L |
Appare nelle tipologie: | 01 - Articolo su rivista |