Purpose: To review cases of central toxic keratopathy (CTK) occurring over a period of 46 days. Setting: Moorfields Eye Hospital, London, United Kingdom. Design: Retrospective consecutive case series. Methods: This was a review of patients with CTK after uneventful laser in situ keratomileusis (LASIK) performed by 1 of 5 surgeons at a single institute. The following parameters were analyzed: corrected distance visual acuity (CDVA), manifest refraction, and central corneal thickness from Scheimpflug pachymetry readings (Pentacam). Results: The cohort consisted of 15 eyes of 9 patients. Thirteen eyes were diagnosed within 7 days after LASIK, while the remaining 2 eyes developed CTK 12 days postoperatively. In 10 eyes, the time to resolution was 1 to 8 months. Five eyes still had residual signs at the last outpatient visit. At the final follow-up, 3 eyes (20%) had a CDVA worse than 0.0 logMAR. Conclusions: Although a rare entity, CTK can occur in clusters. Although a cause was not fully isolated, ultimately each eye achieved excellent CDVA (all better than 0.2 logMAR) at the last follow-up.
Jutley, G., Aiello, F., Robaei, D., Maurino, V. (2014). Central toxic keratopathy after laser in situ keratomileusis. JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 40(12), 1985-1993 [10.1016/j.jcrs.2014.03.030].
Central toxic keratopathy after laser in situ keratomileusis
Aiello, Francesco;
2014-12-01
Abstract
Purpose: To review cases of central toxic keratopathy (CTK) occurring over a period of 46 days. Setting: Moorfields Eye Hospital, London, United Kingdom. Design: Retrospective consecutive case series. Methods: This was a review of patients with CTK after uneventful laser in situ keratomileusis (LASIK) performed by 1 of 5 surgeons at a single institute. The following parameters were analyzed: corrected distance visual acuity (CDVA), manifest refraction, and central corneal thickness from Scheimpflug pachymetry readings (Pentacam). Results: The cohort consisted of 15 eyes of 9 patients. Thirteen eyes were diagnosed within 7 days after LASIK, while the remaining 2 eyes developed CTK 12 days postoperatively. In 10 eyes, the time to resolution was 1 to 8 months. Five eyes still had residual signs at the last outpatient visit. At the final follow-up, 3 eyes (20%) had a CDVA worse than 0.0 logMAR. Conclusions: Although a rare entity, CTK can occur in clusters. Although a cause was not fully isolated, ultimately each eye achieved excellent CDVA (all better than 0.2 logMAR) at the last follow-up.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
