Oxidative stress plays a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV-1) infection causing apoptosis of astroglia cells and neurons. Recent data have shown that oxidative stress is also responsible for the acceleration of human fibroblast telomere shortening in vitro. In the present study we analyzed the potential relations occurring between free radicals formation and telomere length during HIV-1 mediated astroglial death.

Pollicita, M., Muscoli, C., Sgura, A., Biasin, A., Granato, T., Masuelli, L., et al. (2009). Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line. BMC NEUROSCIENCE, 10, 51-51 [10.1186/1471-2202-10-51].

Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line

POLLICITA, MICHELA;PERNO, CARLO FEDERICO;AQUARO, STEFANO
2009-01-01

Abstract

Oxidative stress plays a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV-1) infection causing apoptosis of astroglia cells and neurons. Recent data have shown that oxidative stress is also responsible for the acceleration of human fibroblast telomere shortening in vitro. In the present study we analyzed the potential relations occurring between free radicals formation and telomere length during HIV-1 mediated astroglial death.
2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Analysis of Variance; Apoptosis; Astrocytoma; Telomere; Glutathione; Humans; Cell Line, Tumor; Antiviral Agents; HIV-1; Glutathione Disulfide; Oxidative Stress; Acetylcysteine; Enzyme-Linked Immunosorbent Assay; Microscopy, Electron; Time Factors
Pollicita, M., Muscoli, C., Sgura, A., Biasin, A., Granato, T., Masuelli, L., et al. (2009). Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line. BMC NEUROSCIENCE, 10, 51-51 [10.1186/1471-2202-10-51].
Pollicita, M; Muscoli, C; Sgura, A; Biasin, A; Granato, T; Masuelli, L; Mollace, V; Tanzarella, C; Del Duca, C; Rodinò, P; Perno, Cf; Aquaro, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/28874
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