We present a commentary on the inclusion criteria and outcome measures of the major randomized trials on multiple sclerosis. A qualitative comparison of the characteristics of the enrolled patients is done. The objective is to stimulate a discussion about the need to improve research strategies. The discovery of new drugs studied without personalized criteria does not allow for useful advances in knowledge.

Avolio, C., Centonze, D. (2021). Pivotal Trials in Multiple Sclerosis: Similarities Prove Not to Be Useful. NEUROLOGY AND THERAPY [10.1007/s40120-021-00291-y].

Pivotal Trials in Multiple Sclerosis: Similarities Prove Not to Be Useful

Centonze, Diego
2021-10-30

Abstract

We present a commentary on the inclusion criteria and outcome measures of the major randomized trials on multiple sclerosis. A qualitative comparison of the characteristics of the enrolled patients is done. The objective is to stimulate a discussion about the need to improve research strategies. The discovery of new drugs studied without personalized criteria does not allow for useful advances in knowledge.
30-ott-2021
Pubblicato
Rilevanza internazionale
Commento
Esperti anonimi
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Cladribine
Dimethyl fumarate
Diroximel fumarate
Fingolimod
Ocrelizumab
Ofatumumab
Ozanimod
Ponesimod
Teriflunomide
https://link.springer.com/article/10.1007/s40120-021-00291-y
Avolio, C., Centonze, D. (2021). Pivotal Trials in Multiple Sclerosis: Similarities Prove Not to Be Useful. NEUROLOGY AND THERAPY [10.1007/s40120-021-00291-y].
Avolio, C; Centonze, D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/282247
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