The advanced stages of addiction are characterized by compulsive drug-seeking and drug-taking behaviors despite the loss of the hedonic effect of drug consumption. A pathology of habit forming systems might underlie these features of addiction.

Centonze, D., Costa, C., Rossi, S., Prosperetti, C., Pisani, A., Usiello, A., et al. (2006). Chronic cocaine prevents depotentiation at corticostriatal synapses. BIOLOGICAL PSYCHIATRY, 60(5), 436-443 [10.1016/j.biopsych.2005.11.018].

Chronic cocaine prevents depotentiation at corticostriatal synapses

CENTONZE, DIEGO;PISANI, ANTONIO;BERNARDI, GIORGIO;MERCURI, NICOLA BIAGIO;CALABRESI, PAOLO
2006-09-01

Abstract

The advanced stages of addiction are characterized by compulsive drug-seeking and drug-taking behaviors despite the loss of the hedonic effect of drug consumption. A pathology of habit forming systems might underlie these features of addiction.
1-set-2006
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Cocaine-Related Disorders; Male; Cyclin-Dependent Kinase 5; Synapses; Rats, Wistar; Dopamine Uptake Inhibitors; Rats; Neostriatum; Animals; Receptors, Dopamine D1; Cerebral Cortex; Electric Stimulation; Cocaine; Neuronal Plasticity; Reinforcement (Psychology); Conditioning, Classical; Long-Term Synaptic Depression; Drug Administration Schedule
Centonze, D., Costa, C., Rossi, S., Prosperetti, C., Pisani, A., Usiello, A., et al. (2006). Chronic cocaine prevents depotentiation at corticostriatal synapses. BIOLOGICAL PSYCHIATRY, 60(5), 436-443 [10.1016/j.biopsych.2005.11.018].
Centonze, D; Costa, C; Rossi, S; Prosperetti, C; Pisani, A; Usiello, A; Bernardi, G; Mercuri, Nb; Calabresi, P
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/28050
Citazioni
  • ???jsp.display-item.citation.pmc??? 15
  • Scopus 40
  • ???jsp.display-item.citation.isi??? 38
social impact