To determine whether low-frequency repetitive transcranial magnetic stimulation (rTMS) may modulate l-DOPA-induced dyskinesia (LID) in dyskinetic Parkinson's disease (PD) patients. LID is a severe motor complication in advanced PD patients. The neural mechanisms involved in LID are not clear, and it is apparent that both an excessive decrease in internal pallidus firing and a modification and overactivation of cortical motor and premotor areas are involved in its pathogenesis.

Brusa, L., Versace, V., Koch, G., Iani, C., Stanzione, P., Bernardi, G., et al. (2006). Low frequency rTMS of the SMA transiently ameliorates peak-dose LID in Parkinson's disease. CLINICAL NEUROPHYSIOLOGY, 117(9), 1917-1921 [10.1016/j.clinph.2006.03.033].

Low frequency rTMS of the SMA transiently ameliorates peak-dose LID in Parkinson's disease

STANZIONE, PAOLO;BERNARDI, GIORGIO;CENTONZE, DIEGO
2006-09-01

Abstract

To determine whether low-frequency repetitive transcranial magnetic stimulation (rTMS) may modulate l-DOPA-induced dyskinesia (LID) in dyskinetic Parkinson's disease (PD) patients. LID is a severe motor complication in advanced PD patients. The neural mechanisms involved in LID are not clear, and it is apparent that both an excessive decrease in internal pallidus firing and a modification and overactivation of cortical motor and premotor areas are involved in its pathogenesis.
set-2006
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Analysis of Variance; Dyskinesia, Drug-Induced; Treatment Outcome; Male; Time Factors; Middle Aged; Female; Chi-Square Distribution; Humans; Levodopa; Parkinson Disease; Motor Cortex; Antiparkinson Agents; Aged; Transcranial Magnetic Stimulation
Brusa, L., Versace, V., Koch, G., Iani, C., Stanzione, P., Bernardi, G., et al. (2006). Low frequency rTMS of the SMA transiently ameliorates peak-dose LID in Parkinson's disease. CLINICAL NEUROPHYSIOLOGY, 117(9), 1917-1921 [10.1016/j.clinph.2006.03.033].
Brusa, L; Versace, V; Koch, G; Iani, C; Stanzione, P; Bernardi, G; Centonze, D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/28049
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