Cardiovascular diseases (CVDs) and inflammatory risk indexes are used to calculate the exposure to morbidity. Most of them are suggested by the American College of Cardiology/American Heart Association to predict the risk of CVDs diagnosis in primary prevention, instead of treating the ongoing pathology. Prevention starts from habit changes with the prescription of diet and physical activity (PA). The aim of the study is to investigate the effectiveness of a personalized Mediterranean Diet (MD) and a PA intervention, on the risk indexes Atherogenic Index of Plasma (AIP), Lipid Accumulation Product (LAP) and Fatty Liver Index (FLI) in a population of women at risk of CVDs with different pathological conditions. After treatment, patients achieved the best results in body composition (BC) and laboratory tests. The BC analysis showed a significant reduction of total body Fat Mass (FM). CVDs risk indexes significantly decreased, except for Neutrophil/Lymphocyte (NLR) and Platelet/Lymphocyte Ratios (PLR). The reduction of the CVDs indexes associated with lipid profile was linked to both weight and FM decrease. AIP and LAP were significantly reduced when losing fat mass and body weight, respectively. A personalized MD therapy plus a PA program led to body weight loss, BC remodelling and risk indexes reduction.

Di Renzo, L., Cinelli, G., Dri, M., Gualtieri, P., Attina, A., Leggeri, C., et al. (2020). Mediterranean personalized diet combined with physical activity therapy for the prevention of cardiovascular diseases in Italian women. NUTRIENTS, 12(11), 1-16 [10.3390/nu12113456].

Mediterranean personalized diet combined with physical activity therapy for the prevention of cardiovascular diseases in Italian women

Di Renzo L.;Dri M.;Gualtieri P.;Pujia A.;Chiricolo G.;De Lorenzo A.
2020-01-01

Abstract

Cardiovascular diseases (CVDs) and inflammatory risk indexes are used to calculate the exposure to morbidity. Most of them are suggested by the American College of Cardiology/American Heart Association to predict the risk of CVDs diagnosis in primary prevention, instead of treating the ongoing pathology. Prevention starts from habit changes with the prescription of diet and physical activity (PA). The aim of the study is to investigate the effectiveness of a personalized Mediterranean Diet (MD) and a PA intervention, on the risk indexes Atherogenic Index of Plasma (AIP), Lipid Accumulation Product (LAP) and Fatty Liver Index (FLI) in a population of women at risk of CVDs with different pathological conditions. After treatment, patients achieved the best results in body composition (BC) and laboratory tests. The BC analysis showed a significant reduction of total body Fat Mass (FM). CVDs risk indexes significantly decreased, except for Neutrophil/Lymphocyte (NLR) and Platelet/Lymphocyte Ratios (PLR). The reduction of the CVDs indexes associated with lipid profile was linked to both weight and FM decrease. AIP and LAP were significantly reduced when losing fat mass and body weight, respectively. A personalized MD therapy plus a PA program led to body weight loss, BC remodelling and risk indexes reduction.
2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/49 - SCIENZE TECNICHE DIETETICHE APPLICATE
English
Mediterranean diet
cardiovascular disease
non-communicable disease
obesity
physical activity
Adult
Cardiovascular Diseases
Female
Humans
Italy
Lipids
Middle Aged
Primary Prevention
Prospective Studies
Risk Factors
Risk Reduction Behavior
Weight Loss
Body Composition
Diet, Mediterranean
Exercise
Di Renzo, L., Cinelli, G., Dri, M., Gualtieri, P., Attina, A., Leggeri, C., et al. (2020). Mediterranean personalized diet combined with physical activity therapy for the prevention of cardiovascular diseases in Italian women. NUTRIENTS, 12(11), 1-16 [10.3390/nu12113456].
Di Renzo, L; Cinelli, G; Dri, M; Gualtieri, P; Attina, A; Leggeri, C; Cenname, G; Esposito, E; Pujia, A; Chiricolo, G; Salimei, C; De Lorenzo, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/278286
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