Management of ischemic heart disease in pregnant women is still difficult, as there is little experience with many of the newer treatments such as clopidogrel. The safety of clopidogrel in pregnancy is unknown, especially in combination with aspirin. Its use during gestation has been described in a few case reports. We describe the case of a 36-year-old woman in her 9th week of pregnancy with a history of chronic hypertension, dyslipidemia and CAD, who required antiplatelet treatment. Clopidogrel and aspirin were administrated until one week before delivery and a healthy child was born at 36 weeks of pregnancy by caesarean section, without any complication.

de Santis, M., de Luca, C., Mappa, I., Cesari, E., Mazza, A., Quattrocchi, T., et al. (2011). Clopidogrel treatment during pregnancy: A case report and a review of literature. INTERNAL MEDICINE, 50(16), 1769-1773 [10.2169/internalmedicine.50.5294].

Clopidogrel treatment during pregnancy: A case report and a review of literature

Mappa I.;
2011-01-01

Abstract

Management of ischemic heart disease in pregnant women is still difficult, as there is little experience with many of the newer treatments such as clopidogrel. The safety of clopidogrel in pregnancy is unknown, especially in combination with aspirin. Its use during gestation has been described in a few case reports. We describe the case of a 36-year-old woman in her 9th week of pregnancy with a history of chronic hypertension, dyslipidemia and CAD, who required antiplatelet treatment. Clopidogrel and aspirin were administrated until one week before delivery and a healthy child was born at 36 weeks of pregnancy by caesarean section, without any complication.
2011
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/40 - GINECOLOGIA E OSTETRICIA
English
clopidogrel
pregnancy
coronary artery disease
myocardial infarction
antiplatelet treatment
teratology
Adult
Clopidogrel
Female
Humans
Infant, Newborn
Myocardial Ischemia
Pregnancy
Pregnancy Complications, Cardiovascular
Ticlopidine
Treatment Outcome
de Santis, M., de Luca, C., Mappa, I., Cesari, E., Mazza, A., Quattrocchi, T., et al. (2011). Clopidogrel treatment during pregnancy: A case report and a review of literature. INTERNAL MEDICINE, 50(16), 1769-1773 [10.2169/internalmedicine.50.5294].
de Santis, M; de Luca, C; Mappa, I; Cesari, E; Mazza, A; Quattrocchi, T; Caruso, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/276643
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