Glaucoma is the most common neurodegenerative cause of irreversible blindness worldwide. Restricted caloric regimens are an attractive approach for delaying the progression of neurodegenerative diseases. Here we review the current literature on the effects of caloric restriction on retinal neurons, under physiological and pathological conditions. We focused on autophagy as one of the mechanisms modulated by restricted caloric regimens and involved in the death of retinal ganglion cells (RGCs) over the course of glaucoma.
Adornetto, A., Morrone, L.a., Satriano, A., Lagana, M.l., Licastro, E., Nucci, C., et al. (2020). Effects of caloric restriction on retinal aging and neurodegeneration. In Progress in Brain Research (pp. 189-207). ELSEVIER [10.1016/bs.pbr.2020.07.005].
Effects of caloric restriction on retinal aging and neurodegeneration
Nucci C.;
2020-01-01
Abstract
Glaucoma is the most common neurodegenerative cause of irreversible blindness worldwide. Restricted caloric regimens are an attractive approach for delaying the progression of neurodegenerative diseases. Here we review the current literature on the effects of caloric restriction on retinal neurons, under physiological and pathological conditions. We focused on autophagy as one of the mechanisms modulated by restricted caloric regimens and involved in the death of retinal ganglion cells (RGCs) over the course of glaucoma.| File | Dimensione | Formato | |
|---|---|---|---|
|
ADORNETTO_Effects_19pag.pdf
solo utenti autorizzati
Tipologia:
Versione Editoriale (PDF)
Licenza:
Non specificato
Dimensione
5.62 MB
Formato
Adobe PDF
|
5.62 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
