Objective: The treatment of huge craniopharyngiomas represents a therapeutic challenge for neurosurgeons. Some authors prefer to run the high risks of total removal at primary surgery, while others do not despise subtotal removal in accordance with a multidisciplinary treatment. Methods: We report the case of a 17-year-old girl who underwent subtotal removal (tumour remnant with maximum diameter of 2.5 cm) of a huge cystic craniopharyngioma by frontotemporal approach, followed by early external fractionated radiotherapy by linear accelerator. Serial magnetic resonance imaging during a follow-up period of 5 years showed a progressive marked reduction of the tumour remnant, accompanied by a complete recovery of visual deficits and an almost complete regression of diencephalic disturbances. Conclusions: Subtotal removal followed by early fractionated radiotherapy can be an effective treatment for huge craniopharyngiomas. Such a multidisciplinary treatment may favour tumour control and assure a satisfactory quality of life as well.

Fraioli, M.f., Santoni, R., Fraioli, C., Contratti, F. (2006). Conservative surgical approach and early postoperative radiotherapy in a patient with a huge cystic craniopharyngioma. CHILDS NERVOUS SYSTEM, 22(2), 151-155 [10.1007/s00381-005-1191-8].

Conservative surgical approach and early postoperative radiotherapy in a patient with a huge cystic craniopharyngioma

FRAIOLI, MARIO FRANCESCO;SANTONI, RICCARDO;CONTRATTI, FILIBERTO
2006-01-01

Abstract

Objective: The treatment of huge craniopharyngiomas represents a therapeutic challenge for neurosurgeons. Some authors prefer to run the high risks of total removal at primary surgery, while others do not despise subtotal removal in accordance with a multidisciplinary treatment. Methods: We report the case of a 17-year-old girl who underwent subtotal removal (tumour remnant with maximum diameter of 2.5 cm) of a huge cystic craniopharyngioma by frontotemporal approach, followed by early external fractionated radiotherapy by linear accelerator. Serial magnetic resonance imaging during a follow-up period of 5 years showed a progressive marked reduction of the tumour remnant, accompanied by a complete recovery of visual deficits and an almost complete regression of diencephalic disturbances. Conclusions: Subtotal removal followed by early fractionated radiotherapy can be an effective treatment for huge craniopharyngiomas. Such a multidisciplinary treatment may favour tumour control and assure a satisfactory quality of life as well.
2006
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
English
Con Impact Factor ISI
giant cystic craniopharyngioma; "conservative" surgical approach; postoperative external radiotherapy; endocrinological and visual deficits
Fraioli, M.f., Santoni, R., Fraioli, C., Contratti, F. (2006). Conservative surgical approach and early postoperative radiotherapy in a patient with a huge cystic craniopharyngioma. CHILDS NERVOUS SYSTEM, 22(2), 151-155 [10.1007/s00381-005-1191-8].
Fraioli, Mf; Santoni, R; Fraioli, C; Contratti, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/27039
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