Layered double hydroxides (LDHs) are an emergent class of biocompatible inorganic lamellar nanomaterials that have attracted significant research interest owing to their high surface-to-volume ratio, the capability to accumulate specific molecules, and the timely release to targets. Their unique properties have been employed for applications in organic catalysis, photocatalysis, sensors, drug delivery, and cell biology. Given the widespread contemporary interest in these topics, time-to-time it urges to review the recent progresses. This review aims to summarize the most recent cutting-edge reports appearing in the last years. It firstly focuses on the application of LDHs as catalysts in relevant chemical reactions and as photocatalysts for organic molecule degradation, water splitting reaction, CO2 conversion, and reduction. Subsequently, the emerging role of these materials in biological applications is discussed, specifically focusing on their use as biosensors, DNA, RNA, and drug delivery, finally elucidating their suitability as contrast agents and for cellular di ff erentiation. Concluding remarks and future prospects deal with future applications of LDHs, encouraging researches in better understanding the fundamental mechanisms involved in catalytic and photocatalytic processes, and the molecular pathways that are activated by the interaction of LDHs with cells in terms of both uptake mechanisms and nanotoxicology effects.

Arrabito, G., Bonasera, A., Prestopino, G., Orsini, A., Mattoccia, A., Martinelli, E., et al. (2019). Layered double hydroxides: A toolbox for chemistry and biology. CRYSTALS, 9(7), 361 [10.3390/cryst9070361].

Layered double hydroxides: A toolbox for chemistry and biology

Orsini A.;Mattoccia A.;Martinelli E.;Medaglia P. G.
2019-07-15

Abstract

Layered double hydroxides (LDHs) are an emergent class of biocompatible inorganic lamellar nanomaterials that have attracted significant research interest owing to their high surface-to-volume ratio, the capability to accumulate specific molecules, and the timely release to targets. Their unique properties have been employed for applications in organic catalysis, photocatalysis, sensors, drug delivery, and cell biology. Given the widespread contemporary interest in these topics, time-to-time it urges to review the recent progresses. This review aims to summarize the most recent cutting-edge reports appearing in the last years. It firstly focuses on the application of LDHs as catalysts in relevant chemical reactions and as photocatalysts for organic molecule degradation, water splitting reaction, CO2 conversion, and reduction. Subsequently, the emerging role of these materials in biological applications is discussed, specifically focusing on their use as biosensors, DNA, RNA, and drug delivery, finally elucidating their suitability as contrast agents and for cellular di ff erentiation. Concluding remarks and future prospects deal with future applications of LDHs, encouraging researches in better understanding the fundamental mechanisms involved in catalytic and photocatalytic processes, and the molecular pathways that are activated by the interaction of LDHs with cells in terms of both uptake mechanisms and nanotoxicology effects.
15-lug-2019
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore FIS/03 - FISICA DELLA MATERIA
English
layered double hydroxides
cellular biology
catalysis
DNA
drug delivery
hydrotalcite
osteogenesis
photocatalysis
RNA
https://www.mdpi.com/2073-4352/9/7/361
Arrabito, G., Bonasera, A., Prestopino, G., Orsini, A., Mattoccia, A., Martinelli, E., et al. (2019). Layered double hydroxides: A toolbox for chemistry and biology. CRYSTALS, 9(7), 361 [10.3390/cryst9070361].
Arrabito, G; Bonasera, A; Prestopino, G; Orsini, A; Mattoccia, A; Martinelli, E; Pignataro, B; Medaglia, Pg
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/268074
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