thymosins have been extracted, characterized, and identified from thymus. the thymosins are hormones whose therapeuric applications have seen a recent increase. the action of thymosin α1 is based on the stimulation of the immune response with a large number of results in a variety of pathologies. the absence of a specific receptor prompted us to investigate the direct interaction with membranes, particularly those exposing phosphatidylserine thus contributing to assess the thymosin α1's pleiotropy.
Mandaliti, W., Nepravishta, R., Pica, F., Vallebona, P.s., Garaci, E., Paci, M. (2018). Potential mechanism of thymosin-α1-membrane interactions leading to pleiotropy: experimental evidence and hypotheses. EXPERT OPINION ON BIOLOGICAL THERAPY, 18(sup1), 33-42 [10.1080/14712598.2018.1456527].
Potential mechanism of thymosin-α1-membrane interactions leading to pleiotropy: experimental evidence and hypotheses
Mandaliti, Walter;Pica, Francesca;Garaci, Enrico;Paci, Maurizio
2018-01-01
Abstract
thymosins have been extracted, characterized, and identified from thymus. the thymosins are hormones whose therapeuric applications have seen a recent increase. the action of thymosin α1 is based on the stimulation of the immune response with a large number of results in a variety of pathologies. the absence of a specific receptor prompted us to investigate the direct interaction with membranes, particularly those exposing phosphatidylserine thus contributing to assess the thymosin α1's pleiotropy.| File | Dimensione | Formato | |
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