Vitamin D is a steroid hormone implicated in the regulation of neuronal integrity and many brain functions. Its influence, as a nutrient and a hormone, on the physiopathology of the most common neurodegenerative diseases is continuously emphasized by new studies. This review addresses what is currently known about the action of vitamin D on the nervous system and neurodegenerative diseases such as Multiple Sclerosis, Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral Sclerosis. Further vitamin D research is necessary to understand how the action of this "neuroactive" steroid can help to optimize the prevention and treatment of several neurological diseases.

Morello, M., Pieri, M., Zenobi, R., Talamo, A., Stephan, D., Landel, V., et al. (2020). The influence of vitamin D on neurodegeneration and neurological disorders: A rationale for its physio-pathological actions. CURRENT PHARMACEUTICAL DESIGN, 26(21), 2475-2491 [10.2174/1381612826666200316145725].

The influence of vitamin D on neurodegeneration and neurological disorders: A rationale for its physio-pathological actions

Morello M.;Pieri M.;Zenobi R.;
2020

Abstract

Vitamin D is a steroid hormone implicated in the regulation of neuronal integrity and many brain functions. Its influence, as a nutrient and a hormone, on the physiopathology of the most common neurodegenerative diseases is continuously emphasized by new studies. This review addresses what is currently known about the action of vitamin D on the nervous system and neurodegenerative diseases such as Multiple Sclerosis, Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral Sclerosis. Further vitamin D research is necessary to understand how the action of this "neuroactive" steroid can help to optimize the prevention and treatment of several neurological diseases.
Pubblicato
Rilevanza internazionale
Recensione
Esperti anonimi
Settore BIO/12
eng
Alzheimer's disease
Parkinson's disease
Vitamin D
amyotrophic lateral sclerosis
multiple sclerosis
neurodegenerative diseases.
Humans
Vitamin D
Vitamins
Alzheimer Disease
Multiple Sclerosis
Morello, M., Pieri, M., Zenobi, R., Talamo, A., Stephan, D., Landel, V., et al. (2020). The influence of vitamin D on neurodegeneration and neurological disorders: A rationale for its physio-pathological actions. CURRENT PHARMACEUTICAL DESIGN, 26(21), 2475-2491 [10.2174/1381612826666200316145725].
Morello, M; Pieri, M; Zenobi, R; Talamo, A; Stephan, D; Landel, V; Feron, F; Millet, P
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/266662
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