The complex biochemistry and dynamic structure of mitochondria have prevented them from being prominent pharmacological targets. New mechanistic understanding of cholesterol transport and associated neurosteroidogenesis is providing evidence on therapeutic outcomes in mental disorders that is achievable via mitochondrial pharmacology. This warrants general attention on mitochondrial pharmacology to inform therapies.
Strobbe, D., Campanella, M. (2018). Anxiolytic Therapy: A Paradigm of Successful Mitochondrial Pharmacology. TRENDS IN PHARMACOLOGICAL SCIENCES, 39(5), 437-439 [10.1016/j.tips.2018.02.008].
Anxiolytic Therapy: A Paradigm of Successful Mitochondrial Pharmacology
Campanella, Michelangelo
2018-01-01
Abstract
The complex biochemistry and dynamic structure of mitochondria have prevented them from being prominent pharmacological targets. New mechanistic understanding of cholesterol transport and associated neurosteroidogenesis is providing evidence on therapeutic outcomes in mental disorders that is achievable via mitochondrial pharmacology. This warrants general attention on mitochondrial pharmacology to inform therapies.File in questo prodotto:
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