Knowing the "point of view" of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.

Celardo, I., Pace, L., Cifaldi, L., Gaudio, C., Barnaba, V. (2020). The immune system view of the coronavirus SARS-CoV-2. BIOLOGY DIRECT, 15(1), 30 [10.1186/s13062-020-00283-2].

The immune system view of the coronavirus SARS-CoV-2

Cifaldi, L;
2020-12-01

Abstract

Knowing the "point of view" of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.
dic-2020
Pubblicato
Rilevanza internazionale
Review
Esperti anonimi
Settore MED/04 - PATOLOGIA GENERALE
Settore MEDS-02/A - Patologia generale
English
COVID-19
Coronavirus
Monoclonal antibodies
SARS-CoV-2
Vaccine
Animals
Antibodies, Monoclonal
Autoimmunity
COVID-19
COVID-19 Vaccines
Host-Pathogen Interactions
Humans
Immune Evasion
Immune System
Immunity
Immunity, Innate
Immunotherapy
Celardo, I., Pace, L., Cifaldi, L., Gaudio, C., Barnaba, V. (2020). The immune system view of the coronavirus SARS-CoV-2. BIOLOGY DIRECT, 15(1), 30 [10.1186/s13062-020-00283-2].
Celardo, I; Pace, L; Cifaldi, L; Gaudio, C; Barnaba, V
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/264054
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