Interferon beta (IFNb) is a safe first-line drug commonly used for relapsing-remitting (RR)-MS. Nevertheless, a considerable proportion of patients do not respond to IFNb treatment. Therefore, until now, a number of studies have investigated various markers that could predict the patients who would respond to IFNb therapy. The objective of this study was to identify reliable biomarkers to predict the efficacy of IFNb treatment in MS.

Stampanoni Bassi, M., Drulovic, J., Pekmezovic, T., Iezzi, E., Sica, F., Gilio, L., et al. (2020). Cerebrospinal fluid inflammatory biomarkers predicting interferon-beta response in MS patients. THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS, 13, 1756286420970833 [10.1177/1756286420970833].

Cerebrospinal fluid inflammatory biomarkers predicting interferon-beta response in MS patients

Gentile, Antonietta;Musella, Alessandra;Marfia, Girolama Alessandra;Centonze, Diego;Buttari, Fabio
2020-01-01

Abstract

Interferon beta (IFNb) is a safe first-line drug commonly used for relapsing-remitting (RR)-MS. Nevertheless, a considerable proportion of patients do not respond to IFNb treatment. Therefore, until now, a number of studies have investigated various markers that could predict the patients who would respond to IFNb therapy. The objective of this study was to identify reliable biomarkers to predict the efficacy of IFNb treatment in MS.
2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
NEDA-3
cerebrospinal fluid (CSF)
clinically isolated syndrome (CIS)
interferon beta (IFNb)
macrophage inflammatory protein (MIP)-1α
platelet-derived growth factor (PDGF)
relapsing-remitting (RR)-MS
https://journals.sagepub.com/doi/10.1177/1756286420970833?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub 0pubmed
Stampanoni Bassi, M., Drulovic, J., Pekmezovic, T., Iezzi, E., Sica, F., Gilio, L., et al. (2020). Cerebrospinal fluid inflammatory biomarkers predicting interferon-beta response in MS patients. THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS, 13, 1756286420970833 [10.1177/1756286420970833].
Stampanoni Bassi, M; Drulovic, J; Pekmezovic, T; Iezzi, E; Sica, F; Gilio, L; Gentile, A; Musella, A; Mandolesi, G; Furlan, R; Finardi, A; Marfia, Ga; Bellantonio, P; Fantozzi, R; Centonze, D; Buttari, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/261836
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