This study has a twofold aim: 1) to investigate whether protein expression and enzyme activity of phosphodiesterase 5 (PDE5) can be detected in human myometrium and undergo changes in relation to the presence of pregnancy and/or labor; 2) to evaluate whether PDE5 expression and activity in myometrial cells can be influenced by human chorionic gonadotropin (HCG).

Belmonte, A., Ticconi, C., DOLCI IANNINI, S., Giorgi, M., Zicari, A., Lenzi, A., et al. (2005). Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 12(8), 570-577 [10.1016/j.jsgi.2005.09.002].

Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin

TICCONI, CARLO;DOLCI IANNINI, SUSANNA;JANNINI, EMMANUELE ANGELO FRANCESCO;PICCIONE, EMILIO
2005-12-01

Abstract

This study has a twofold aim: 1) to investigate whether protein expression and enzyme activity of phosphodiesterase 5 (PDE5) can be detected in human myometrium and undergo changes in relation to the presence of pregnancy and/or labor; 2) to evaluate whether PDE5 expression and activity in myometrial cells can be influenced by human chorionic gonadotropin (HCG).
dic-2005
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/16 - ANATOMIA UMANA
English
Con Impact Factor ISI
Dose-Response Relationship, Drug; Labor, Obstetric; Humans; 3',5'-Cyclic-GMP Phosphodiesterases; Purines; Chorionic Gonadotropin; Cyclic Nucleotide Phosphodiesterases, Type 5; Pregnancy; Cyclic GMP; Piperazines; Phosphoric Diester Hydrolases; Gene Expression Regulation, Enzymologic; Cells, Cultured; Sulfones; Muscle Contraction; Myometrium; Immunohistochemistry; Bucladesine; Female
Belmonte, A., Ticconi, C., DOLCI IANNINI, S., Giorgi, M., Zicari, A., Lenzi, A., et al. (2005). Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 12(8), 570-577 [10.1016/j.jsgi.2005.09.002].
Belmonte, A; Ticconi, C; DOLCI IANNINI, S; Giorgi, M; Zicari, A; Lenzi, A; Jannini, Eaf; Piccione, E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/25758
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