Psoriasis is a multisystemic inflammatory disease with a significant burden in terms of disability and reduced quality of life. The interrelations between disease severity, psychological well-being, and disability and/or health-related quality of life (HRQOL) of psoriatic patients are not fully understood. The aim of the study was to assess the relative role of disease severity, depressive symptoms, and insecure attachment in predicting disability and HRQOL in 105 patients with psoriasis. Objective measures of disease severity included the Body Surface Area (BSA), the Psoriasis Area and Severity Index (PASI), and the Pain Visual Analog Scale (pain-VAS). The Sheehan Disability Scale (SDS). The Dermatology Life Quality Index (DLQI). Multivariate hierarchical regression analysis showed that a preoccupied style of attachment and the presence of depressive symptoms were predictors of disability and HRQOL over and above the contribution of demographic and clinical variables. The inclusion of attachment and depression into multivariate regression models improved substantially the prediction of disability and HRQOL. Conversely, the predictive utility of objective indicators of disease severity was scarce and only the pain-VAS emerged as a significant predictor of disability whereas there were no significant correlations between HRQOL and any of the objective indicators of disease severity. Measures capturing patients' perspectives of the functional impact of disease should be routinely included in the clinical assessment of psoriasis.

Esposito, M., Giunta, A., Nanni, R.c., Criscuolo, S., Manfreda, V., Del Duca, E., et al. (2020). Depressive symptoms and insecure attachment predict disability and quality of life in psoriasis independently from disease severity. ARCHIVES OF DERMATOLOGICAL RESEARCH [10.1007/s00403-020-02116-8].

Depressive symptoms and insecure attachment predict disability and quality of life in psoriasis independently from disease severity

Giunta, Alessandro;Bianchi, Luca;Troisi, Alfonso
2020

Abstract

Psoriasis is a multisystemic inflammatory disease with a significant burden in terms of disability and reduced quality of life. The interrelations between disease severity, psychological well-being, and disability and/or health-related quality of life (HRQOL) of psoriatic patients are not fully understood. The aim of the study was to assess the relative role of disease severity, depressive symptoms, and insecure attachment in predicting disability and HRQOL in 105 patients with psoriasis. Objective measures of disease severity included the Body Surface Area (BSA), the Psoriasis Area and Severity Index (PASI), and the Pain Visual Analog Scale (pain-VAS). The Sheehan Disability Scale (SDS). The Dermatology Life Quality Index (DLQI). Multivariate hierarchical regression analysis showed that a preoccupied style of attachment and the presence of depressive symptoms were predictors of disability and HRQOL over and above the contribution of demographic and clinical variables. The inclusion of attachment and depression into multivariate regression models improved substantially the prediction of disability and HRQOL. Conversely, the predictive utility of objective indicators of disease severity was scarce and only the pain-VAS emerged as a significant predictor of disability whereas there were no significant correlations between HRQOL and any of the objective indicators of disease severity. Measures capturing patients' perspectives of the functional impact of disease should be routinely included in the clinical assessment of psoriasis.
Online ahead of print
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/35
English
Attachment style
Depression
Disability
Psoriasis
Quality of life
Esposito, M., Giunta, A., Nanni, R.c., Criscuolo, S., Manfreda, V., Del Duca, E., et al. (2020). Depressive symptoms and insecure attachment predict disability and quality of life in psoriasis independently from disease severity. ARCHIVES OF DERMATOLOGICAL RESEARCH [10.1007/s00403-020-02116-8].
Esposito, M; Giunta, A; Nanni, Rc; Criscuolo, S; Manfreda, V; Del Duca, E; Bianchi, L; Troisi, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/255405
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