Corrected QT (QTc) interval prolongation is often associated with use of first-generation antipsychotics (FGAs). However, other factors require appropriate consideration, including age and gender, the role of other known medications associated with QTc prolongation, and severe comorbid conditions, such as co-occurring alcohol abuse/dependence. We aimed to study potential mediating roles of different, related, candidate variables on QTc.

Carrà, G., Crocamo, C., Bartoli, F., Lax, A., Tremolada, M., Lucii, C., et al. (2016). First-generation antipsychotics and QTc: any role for mediating variables?. HUMAN PSYCHOPHARMACOLOGY, 31(4), 313-318 [10.1002/hup.2540].

First-generation antipsychotics and QTc: any role for mediating variables?

Ribolsi, Michele
2016-07-01

Abstract

Corrected QT (QTc) interval prolongation is often associated with use of first-generation antipsychotics (FGAs). However, other factors require appropriate consideration, including age and gender, the role of other known medications associated with QTc prolongation, and severe comorbid conditions, such as co-occurring alcohol abuse/dependence. We aimed to study potential mediating roles of different, related, candidate variables on QTc.
lug-2016
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/25 - PSICHIATRIA
English
QT prolongation; alcohol; antipsychotic agents; drug therapy combination; risk factors; Adult; Antipsychotic Agents; Cross-Sectional Studies; Electrocardiography; Female; Heart Rate; Humans; Italy; Long QT Syndrome; Male; Mental Disorders; Middle Aged
Carrà, G., Crocamo, C., Bartoli, F., Lax, A., Tremolada, M., Lucii, C., et al. (2016). First-generation antipsychotics and QTc: any role for mediating variables?. HUMAN PSYCHOPHARMACOLOGY, 31(4), 313-318 [10.1002/hup.2540].
Carrà, G; Crocamo, C; Bartoli, F; Lax, A; Tremolada, M; Lucii, C; Martinotti, G; Nosè, M; Bighelli, I; Ostuzzi, G; Castellazzi, M; Clerici, M; Barbui, C; Ribolsi, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/251380
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